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Synthesis of antitumor pyridine and pyridazine N-oxides having (2-chloroethyl)nitrosoureidomethyl and bis(2-chlorethyl)-aminomethyl groups. 1978

S Kamiya, and M Miyahara, and S Sueyoshi, and I Suzuki, and S Odashima

UI MeSH Term Description Entries
D009588 Nitrogen Mustard Compounds A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens. Compounds, Nitrogen Mustard,Mustard Compounds, Nitrogen
D009607 Nitrosourea Compounds A class of compounds in which the core molecule is R-NO, where R is UREA. Compounds, Nitrosourea
D011724 Pyridazines Six-membered rings with two adjacent nitrogen atoms also called 1,2-diazine.
D011725 Pyridines Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
D003497 Cyclic N-Oxides Heterocyclic compounds in which an oxygen is attached to a cyclic nitrogen. Heterocyclic N-Oxides,Cyclic N Oxides,Heterocyclic N Oxides,N Oxides, Cyclic,N-Oxides, Cyclic,N-Oxides, Heterocyclic,Oxides, Cyclic N
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000970 Antineoplastic Agents Substances that inhibit or prevent the proliferation of NEOPLASMS. Anticancer Agent,Antineoplastic,Antineoplastic Agent,Antineoplastic Drug,Antitumor Agent,Antitumor Drug,Cancer Chemotherapy Agent,Cancer Chemotherapy Drug,Anticancer Agents,Antineoplastic Drugs,Antineoplastics,Antitumor Agents,Antitumor Drugs,Cancer Chemotherapy Agents,Cancer Chemotherapy Drugs,Chemotherapeutic Anticancer Agents,Chemotherapeutic Anticancer Drug,Agent, Anticancer,Agent, Antineoplastic,Agent, Antitumor,Agent, Cancer Chemotherapy,Agents, Anticancer,Agents, Antineoplastic,Agents, Antitumor,Agents, Cancer Chemotherapy,Agents, Chemotherapeutic Anticancer,Chemotherapy Agent, Cancer,Chemotherapy Agents, Cancer,Chemotherapy Drug, Cancer,Chemotherapy Drugs, Cancer,Drug, Antineoplastic,Drug, Antitumor,Drug, Cancer Chemotherapy,Drug, Chemotherapeutic Anticancer,Drugs, Antineoplastic,Drugs, Antitumor,Drugs, Cancer Chemotherapy
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

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S Kamiya, and M Miyahara, and S Sueyoshi, and I Suzuki, and S Odashima
[Tumour inhibitory N-(bis--(2-chlorethyl)-aminomethyl)-urethanes (author's transl)].
November 1975, Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology,
S Kamiya, and M Miyahara, and S Sueyoshi, and I Suzuki, and S Odashima
[Synthesis and tumor inhibiting effect of N-(bis(2-chlorethyl)-aminomethyl)-amides. 21. Cytostatic agents].
January 1973, Archiv der Pharmazie,
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In vivo antitumor activity of 5-hydroxy-6-[N,N-bis(2-chloroethyl)aminomethyl]naphthalene-1,8- carbolactone.
January 1992, Die Pharmazie,
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[TUMOR CHEMOTHERAPY. XXIX. STUDIES ON BIS-(BETA-CHLOROETHYL)-AMINOMETHYLPHENYLALANINE. 2. SYNTHESIS OF 2-BIS-(BETA-CHLOROETHYL)-AMINOMETHYL-5-NITROPHENYLALANINE].
April 1965, Yao xue xue bao = Acta pharmaceutica Sinica,
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Synthesis and evaluation of antitumor activity of 1-[N, N-bis(2-chloroethyl) sulfamoylphenyl]-3,3-dialkyltriazenes.
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HEXAHYDROPYRIMIDINES. IV. SYNTHESIS OF 2-(4-(N,N-BIS(2-CHLOROETHYL)AMINO)ARYL)-1,3-BIS(ARALKYL)HEXAHYDROPYRIMIDINES AS ANTITUMOR AGENTS.
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[bis(beta-chloroethyl)-aminomethyl]-azobenzene].
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[Tumour chemotherapy. XXXIX Synthesis of 2-methyl-5-bis (beta-chloroethyl) aminophenylalanine and 2-bis (beta-chloroethyl)-aminomethyl-5-nitrophenylalanine (author's transl)].
November 1979, Yao xue xue bao = Acta pharmaceutica Sinica,
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Synthesis and evaluation of esters of N,N-bis(2-chloroethyl)-p-aminophenol and N,N-bis(2-bromoethyl)-p-aminophenol as potential antitumor agents.
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