Biomaterial Database

Lobular carcinoma of the breast can be managed by breast-conserving therapy. 1995

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

Department of Surgery, University Hospital of South Manchester, UK.

There has been a reluctance to treat patients with invasive lobular carcinoma by breast-conserving therapy because of the possibility of increased rates of local recurrence. This study is a retrospective review of 226 patients with pure invasive lobular carcinoma 4 cm or less treated by breast conservation therapy or mastectomy. Local relapse occurred in four of 52 patients (8 per cent) after breast conservation compared with 21 of 174 (12 per cent) after mastectomy. Breast conservation for invasive lobular carcinoma did not result in a higher incidence of local relapse and patients with invasive lobular and ductal carcinomas may be managed in a similar fashion.

UI	MeSH Term	Description	Entries
D008197	Lymph Node Excision	Surgical excision of one or more lymph nodes. Its most common use is in cancer surgery. (From Dorland, 28th ed, p966)	Lymph Node Dissection,Lymphadenectomy,Dissection, Lymph Node,Dissections, Lymph Node,Excision, Lymph Node,Excisions, Lymph Node,Lymph Node Dissections,Lymph Node Excisions,Lymphadenectomies,Node Dissection, Lymph,Node Dissections, Lymph
D008408	Mastectomy	Surgical procedure to remove one or both breasts.	Mammectomy,Mammectomies,Mastectomies
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009364	Neoplasm Recurrence, Local	The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.	Local Neoplasm Recurrence,Local Neoplasm Recurrences,Locoregional Neoplasm Recurrence,Neoplasm Recurrence, Locoregional,Neoplasm Recurrences, Local,Recurrence, Local Neoplasm,Recurrence, Locoregional Neoplasm,Recurrences, Local Neoplasm,Locoregional Neoplasm Recurrences,Neoplasm Recurrences, Locoregional,Recurrences, Locoregional Neoplasm
D001943	Breast Neoplasms	Tumors or cancer of the human BREAST.	Breast Cancer,Breast Tumors,Cancer of Breast,Breast Carcinoma,Cancer of the Breast,Human Mammary Carcinoma,Malignant Neoplasm of Breast,Malignant Tumor of Breast,Mammary Cancer,Mammary Carcinoma, Human,Mammary Neoplasm, Human,Mammary Neoplasms, Human,Neoplasms, Breast,Tumors, Breast,Breast Carcinomas,Breast Malignant Neoplasm,Breast Malignant Neoplasms,Breast Malignant Tumor,Breast Malignant Tumors,Breast Neoplasm,Breast Tumor,Cancer, Breast,Cancer, Mammary,Cancers, Mammary,Carcinoma, Breast,Carcinoma, Human Mammary,Carcinomas, Breast,Carcinomas, Human Mammary,Human Mammary Carcinomas,Human Mammary Neoplasm,Human Mammary Neoplasms,Mammary Cancers,Mammary Carcinomas, Human,Neoplasm, Breast,Neoplasm, Human Mammary,Neoplasms, Human Mammary,Tumor, Breast
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D000369	Aged, 80 and over	Persons 80 years of age and older.	Oldest Old

Related Publications

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

Examination of breast conserving therapy in lobular carcinoma.

January 2004, Breast cancer (Tokyo, Japan),

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

Invasive lobular carcinoma and breast conserving therapy: implications for the pathologist.

January 2003, The breast journal,

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

Atypical Lobular Hyperplasia and Classic Lobular Carcinoma In Situ Can Be Safely Managed Without Surgical Excision.

March 2022, Annals of surgical oncology,

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

Invasive lobular carcinoma of the breast: local recurrence after breast-conserving therapy by subtype approximation and surgical margin.

January 2015, Breast cancer research and treatment,

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

Breast-conserving therapy can be offered to women with prior breast augmentation.

August 2020, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology,

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

The impact of margin status in breast-conserving therapy for lobular carcinoma is age related.

February 2010, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology,

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

Selecting patients for breast-conserving therapy: the importance of lobular histology.

June 2006, Cancer,

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

[Lobular carcinoma in situ as a component of breast cancer points to no contraindication for breast-conserving therapy].

January 2001, Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al],

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

Breast conserving treatment for ductal carcinoma in situ in the elderly: can radiation therapy be avoided? Our experience.

January 2014, International journal of surgery (London, England),

P A Holland, and A Shah, and A Howell, and A D Baildam, and N J Bundred

Invasive Lobular Breast Carcinoma Can Be a Challenging Diagnosis Without the Use of Tumor Markers.

May 2020, Cureus,