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Hepatitis E virus (HEV) is a polyadenylated, positive-stranded RNA virus which is a major cause of enterically transmitted non-A, non-B hepatitis in many developing countries. The viral genome contains three different open reading frames (ORFs): ORF1, which is believed to encode nonstructural proteins, and ORF2 and ORF3, which are believed to encode structural proteins. The full-length putative structural proteins encoded by ORF2 and ORF3 of HEV have been cloned and expressed in recombinant vaccinia virus. Proteins encoded by ORF2 and ORF3 when expressed in vaccinia virus are recognized by pooled sera obtained from individuals with acute hepatitis E. Vaccinia-expressed viral gene products of HEV will have utility in characterizing the cell-mediated immune response to HEV.
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
August 2012,
Journal of virology,
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
January 1990,
Archives of virology,
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
August 1993,
Journal of clinical microbiology,
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
January 1986,
Nature,
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
December 1987,
Journal of virology,
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
April 1997,
AIDS research and human retroviruses,
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
January 1994,
Archives of virology,
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
January 1996,
Revista do Instituto de Medicina Tropical de Sao Paulo,
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
February 1998,
Protein expression and purification,
M Carl, and
S N Isaacs, and
M Kaur, and
J He, and
A W Tam, and
P O Yarbough, and
G R Reyes
June 1993,
Immunology letters,
