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Renal cortical and papillary perfusions were assessed by laser-Doppler flowmetry and autoregulatory indices. There was cortical autoregulation (autoregulatory index of 0.31 +/- 0.08) in Wistar from 160 to 100 mm Hg, but not in the papilla, which was abolished by nitrendipine, 0.125 and 0.25 micrograms kg-1 min-1. In SHRSP the cortex, but not the papilla, exhibited autoregulation from 180 to 120 mm Hg (autoregulatory index of 0.27 +/- 0.10) but not during low and high doses of nitrendipine. The non-clipped kidney cortex of 2K1C Goldblatt rats autoregulated from 190 to 130 mm Hg (autoregulatory index of 0.20 +/- 0.13), but was inhibited only by the higher dose of nitrendipine. In mature Wistar and SHRSP cortical autoregulation is blocked effectively by nitrendipine whereas the 2K1C Goldblatt hypertensive rats are relatively resistant.
C Huang, and
E J Johns
June 1988,
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C Huang, and
E J Johns
January 1981,
Hypertension (Dallas, Tex. : 1979),
C Huang, and
E J Johns
March 1979,
Circulation research,
C Huang, and
E J Johns
June 1999,
Biulleten' eksperimental'noi biologii i meditsiny,
C Huang, and
E J Johns
March 1998,
IEEE transactions on bio-medical engineering,
C Huang, and
E J Johns
March 1987,
The American journal of physiology,
C Huang, and
E J Johns
January 1993,
Renal failure,
C Huang, and
E J Johns
November 2007,
American journal of physiology. Renal physiology,
C Huang, and
E J Johns
September 1987,
Japanese circulation journal,
C Huang, and
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August 1985,
Experimental and molecular pathology,
