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The effect of radiotherapy on peripheral blood lymphocytes (PBL) of lung cancer and the effect of BCG cell-wall skeleton (BCG-CWS) on recovery of impaired PBL were examined. A remarkable depression of the absolute number of E- or EAC-rosette cells and of the response of PBL to mitogens were observed immediately after radiotherapy, and these continued for several months. With BCG-CWS immunotherapy, the response of PBL to phytohemagglutinin recovered rapidly, compared with non-vaccinated patients. The response of PBL to pokeweed mitogen seemed to give similar results. These results suggested that BCG-CWS injection to the patient receiving radiotherapy was effective for recovery of T-cell response.
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T Yoshimoto, and
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M Itoh, and
T Masuno, and
M Namba, and
T Ogura, and
F Hirao, and
I Azuma, and
Y Yamamura
December 1976,
Gan,
H Nishikawa, and
S Yasaki, and
T Yoshimoto, and
M Sakatani, and
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T Masuno, and
M Namba, and
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F Hirao, and
I Azuma, and
Y Yamamura
April 1979,
Cancer,
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T Masuno, and
M Namba, and
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F Hirao, and
I Azuma, and
Y Yamamura
October 1977,
Kekkaku : [Tuberculosis],
H Nishikawa, and
S Yasaki, and
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Y Yamamura
November 1977,
Nihon Kyobu Shikkan Gakkai zasshi,
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May 1978,
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
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April 1983,
Nihon Geka Gakkai zasshi,
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