Biomaterial Database

Pathogenic effects of Fusarium sulphureum, Fusarium solani Var. coeruleum and dry rot affected potatoes on the internal organs of rats. 1993

T Rotkiewicz, and J Szarek, and S Tarkowian

Department of Forensic Veterinary Medicine, University of Agriculture and Technology, Olsztyn, Poland.

Rats of the Wistar race were used in toxicological experiments involving Fusarium sulphureum Schl., F. solani var. coeruleum (Sacc.) Booth and potatoes damaged by these fungi. The in vivo and postmortem studies revealed that both fungi and effected tubers had hepatotoxic and nephrotoxic effects on the animals. Morphological changes in the internal organs were mainly manifested by disturbances in blood circulation and regressive metamorphosis. These changes intensified proportionally to the dose of fungi and diseased potatoes in the feed used. Fusarium solani was more pathogenic than F. sulphureum. No teratogenic effect was observed, although addition of the fungi and infested potatoes into the feeds decreased the reproductive ability of rats and caused a decrease in foetal body weight as well as haematomae in foetuses.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D011198	Solanum tuberosum	A plant species of the genus SOLANUM, family SOLANACEAE. The starchy roots are used as food. SOLANINE is found in green parts.	Potatoes,Potato,Solanum tuberosums,tuberosum, Solanum,tuberosums, Solanum
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D005260	Female		Females
D005506	Food Contamination	The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.	Food Adulteration,Adulteration, Food,Adulterations, Food,Contamination, Food,Contaminations, Food,Food Adulterations,Food Contaminations
D005517	Foodborne Diseases	Acute illnesses, usually affecting the GASTROINTESTINAL TRACT, brought on by consuming contaminated food or beverages. Most of these diseases are infectious, caused by a variety of bacteria, viruses, or parasites that can be foodborne. Sometimes the diseases are caused by harmful toxins from the microbes or other chemicals present in the food. Especially in the latter case, the condition is often called food poisoning.	Food Poisoning,Food-borne Disease,Food-borne Illness,Foodborne Disease,Foodborne Illness,Food-borne Diseases,Food-borne Illnesses,Foodborne Illnesses,Poisoning, Food,Disease, Food-borne,Disease, Foodborne,Food Poisonings,Food borne Disease,Food borne Diseases,Food borne Illness,Food borne Illnesses,Illness, Food-borne,Illness, Foodborne,Illnesses, Foodborne
D005670	Fusarium	A mitosporic Hypocreales fungal genus, various species of which are important parasitic pathogens of plants and a variety of vertebrates. Teleomorphs include GIBBERELLA.	Fusariums
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D017208	Rats, Wistar	A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.	Wistar Rat,Rat, Wistar,Wistar Rats
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus