-transparent.png){kind=logo}
The chemotactic cytokine RANTES (Regulated on Activation, Normal T-cell Expressed and Secreted) is a potent chemoattractant and activator of a number of leukocytes, with a molecular mass of 8 kDa. Crystals of this protein have been grown from 100 mM sodium acetate buffer (pH 4.6) containing 200 mM magnesium acetate, with 20% (w/v) PEG 4000 and 6% (v/v) glycerol. The crystals grow as thick rods, which diffract to at least 1.8 A resolution on a rotating anode X-ray source. The crystals belong to space group p2(1)2(1)2(1) with unit cell dimensions a = 95.14 A, b = 57.58 A and c = 24.01 A with alpha = beta = gamma = 90 degrees. The asymmetric unit contains two molecules of the RANTES monomer, with a VM of 2.0 A(3)/Da.
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
March 2002,
Acta crystallographica. Section D, Biological crystallography,
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
September 1999,
Acta crystallographica. Section D, Biological crystallography,
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
August 1970,
Proceedings of the National Academy of Sciences of the United States of America,
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
July 1996,
Proteins,
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
January 1997,
Acta crystallographica. Section D, Biological crystallography,
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
January 2000,
Acta crystallographica. Section D, Biological crystallography,
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
February 1993,
Journal of molecular biology,
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
January 1996,
Journal of structural biology,
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
January 1991,
Proteins,
J P Shaw, and
G Kryger, and
A Cleasby, and
A Wonacott, and
C A Power, and
A E Proudfoot, and
T N Wells
October 1994,
Journal of molecular biology,
