[The diagnostic value of anti-HCV test in HCV infection]. 1994

F H Liu, and G S Tian, and X X Fu
First School of Clinical Medicine, Beijing Medical University.

Two hundred and ninety-six samples of patient serum and 28 samples of donor serum were tested for anti-HCV with second generation domestic made testing kit, and for HCV RNA with PCR assay. The aim of this study is to assess the diagnostic value of anti-HCV test in HCV infection and to discuss its value in screening of donors. The results were as follows HCV RNA was detected in 81.6% of the anti-HCV positive patient samples and in 21.7% of the anti-HCV negative patient samples. HCV RNA was not detected in 28 anti-HCV negative donors. These results reveals that positive anti-HCV is of high diagnostic value in HCV infection. Anti-HCV negative could not exclude HCV infection for samples suspected of HCV infection. However, screening donors with anti-HCV probably decreases HCV RNA positive rate considerably.

UI MeSH Term Description Entries
D001782 Blood Donors Individuals supplying blood or blood components for transfer to histocompatible recipients. Blood Donor,Donor, Blood,Donors, Blood
D006508 Hepatitis Antibodies Immunoglobulins raised by any form of viral hepatitis; some of these antibodies are used to diagnose the specific kind of hepatitis. Antibodies, Hepatitis
D006526 Hepatitis C INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown. Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted,Parenterally-Transmitted Non-A, Non-B Hepatitis,PT-NANBH,Parenterally Transmitted Non A, Non B Hepatitis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012367 RNA, Viral Ribonucleic acid that makes up the genetic material of viruses. Viral RNA
D016174 Hepacivirus A genus of FLAVIVIRIDAE causing parenterally-transmitted HEPATITIS C which is associated with transfusions and drug abuse. Hepatitis C virus is the type species. Hepatitis C virus,Hepatitis C-Like Viruses,Hepaciviruses,Hepatitis C Like Viruses,Hepatitis C viruses,Hepatitis C-Like Virus
D018937 Hepatitis C Antibodies Antibodies to the HEPATITIS C ANTIGENS including antibodies to envelope, core, and non-structural proteins. Anti-HCV Antibodies,Anti-Hepatitis C Virus Antibodies,HCV Antibodies,Hepatitis C Virus Antibodies,Anti HCV Antibodies,Anti Hepatitis C Virus Antibodies

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