-transparent.png){kind=logo}
We determined the serum amyloid A protein (SAA) levels in patients with non-insulin-dependent diabetes mellitus (NIDDM), and investigated the possible association between SAA and the complications of NIDDM. The concentrations of SAA were measured in the plasma of 105 patients with NIDDM (52 men and 53 women, age mean +/- SD, 61 +/- 13 years) and 91 healthy subjects (37 men and 54 women, aged 57 +/- 11 years). SAA concentrations were assayed by enzyme-linked immunosorbent assay. SAA concentrations in the patients with NIDDM were significantly higher than those in healthy subjects (2.1 +/- 1.3 vs. 1.2 +/- 0.5 mg/L). There were no obvious relationships between SAA levels and duration of diabetes, type of therapy, or control of blood sugar in the patients with NIDDM. However, SAA levels in patients with NIDDM increased significantly, with increase of urinary albumin excretion (p = 0.027). The increase of SAA in the patients with NIDDM did not influence the serum concentrations of lipid or lipoprotein. The SAA concentration in NIDDM was unrelated to the type of treatment, but seemed to be related to the development of diabetic nephropathy.
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
August 1986,
Nederlands tijdschrift voor geneeskunde,
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
January 1997,
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University,
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
August 1989,
The American journal of clinical nutrition,
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
June 1998,
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics,
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
December 1982,
African journal of medicine and medical sciences,
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
March 1991,
JAMA,
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
January 1991,
Problemy endokrinologii,
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
March 1994,
Clinica chimica acta; international journal of clinical chemistry,
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
April 1997,
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics,
Y Kumon, and
T Suehiro, and
T Itahara, and
Y Ikeda, and
K Hashimoto
October 1999,
Journal of Korean medical science,
