Biomaterial Database

[Use of the mass spectrometer as a specific detector in the analysis of alcoholic beverages by gas-liquid chromatography]. 1978

P A Liddle, and P de Smedt

The technique of selected ion monitoring (SIM) allows the mass spectrometer to be used as a selective detector when coupled to a gas chromatograph. The addition of a data acquisition system enables the selective quantitative determination of compounds to be made when present at low levels in a complex mixture. The detection limit of a compound may be lowered by 2 or 3 orders of magnitude, since the instrument is set to one or more ions which are specific for the compound(s) to be measured, for the maximum amount of time. This lowering of the detection limit and increase in selectivity makes it possible not only to determine compounds at ppb levels, but also to carry out rapid and selective determinations of compounds at the ppm level, using a smaller sample and a minimum of preliminary sample concentration. A fuller description of the principles of SIM is given. This technique has already found wide application in medical and environmental fields, and some examples of its application to alcoholic beverages are given: detection and determination of possible contaminants, such as phthalate, esters residual monomers from plastic materials (styrene, vinyl chloride), and traces of pesticides; determination of certain non-volatile compounds in wines; and the selective determination of certain compounds for which levels in finished products are limited such as the thujones, safrole, beta-asarone, and coumarine.

UI	MeSH Term	Description	Entries
D010573	Pesticide Residues	Pesticides or their breakdown products remaining in the environment following their normal use or accidental contamination.	Pesticide Residue,Residue, Pesticide,Residues, Pesticide
D010969	Plastics	Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	Plastic
D002849	Chromatography, Gas	Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.	Chromatography, Gas-Liquid,Gas Chromatography,Chromatographies, Gas,Chromatographies, Gas-Liquid,Chromatography, Gas Liquid,Gas Chromatographies,Gas-Liquid Chromatographies,Gas-Liquid Chromatography
D003374	Coumarins	Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid.	1,2-Benzopyrone Derivatives,1,2-Benzopyrones,Coumarin Derivative,Coumarine,1,2-Benzo-Pyrones,Benzopyran-2-ones,Coumarin Derivatives,Coumarines,1,2 Benzo Pyrones,1,2 Benzopyrone Derivatives,1,2 Benzopyrones,Benzopyran 2 ones,Derivative, Coumarin,Derivatives, 1,2-Benzopyrone,Derivatives, Coumarin
D005506	Food Contamination	The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.	Food Adulteration,Adulteration, Food,Adulterations, Food,Contamination, Food,Contaminations, Food,Food Adulterations,Food Contaminations
D000434	Alcoholic Beverages	Drinkable liquids containing ETHANOL.	Alcoholic Beverage,Beverage, Alcoholic,Beverages, Alcoholic
D012451	Safrole	A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).	Shikimol,4-Allyl-1,2-methylenedioxybenzene,Safrol,4 Allyl 1,2 methylenedioxybenzene,4-Allyl-1,2-methylenedioxybenzenes,Safroles,Safrols,Shikimols
D013058	Mass Spectrometry	An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.	Mass Spectroscopy,Spectrometry, Mass,Spectroscopy, Mass,Spectrum Analysis, Mass,Analysis, Mass Spectrum,Mass Spectrum Analysis,Analyses, Mass Spectrum,Mass Spectrum Analyses,Spectrum Analyses, Mass
D013343	Styrenes	Derivatives and polymers of styrene. They are used in the manufacturing of synthetic rubber, plastics, and resins. Some of the polymers form the skeletal structures for ion exchange resin beads.
D014752	Vinyl Chloride	A gas that has been used as an aerosol propellant and is the starting material for polyvinyl resins. Toxicity studies have shown various adverse effects, particularly the occurrence of liver neoplasms.	Chloroethylene,Chloride, Vinyl