Oral contraceptive use and breast cancer risk among African-American women. 1995

J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
Slone Epidemiology Unit, School of Public Health, Boston University School of Medicine, Brookline, MA, USA.

Recent epidemiologic studies, most of them in predominantly White populations, have suggested that long duration of oral contraceptive (OC) use may increase the risk of breast cancer at young ages. We assessed the relationship of OC use to the risk of breast cancer in African-American women aged 25 to 59 years, using interview data from a multipurpose hospital-based case-control study. Five hundred and twenty-four cases hospitalized for invasive breast cancer were compared with 1,021 controls with nonmalignant conditions unrelated to OC use. Relative risks (RR) and 95 percent confidence intervals (CI) were estimated relative to a reference category of use for less than 12 months; potential confounders were controlled by multiple logistic regression analysis. Among women under age 45, three or more years of OC use was associated with an increased risk of breast cancer: the RR estimate was 2.8 (CI = 1.5-5.0) for three to four years of use, and declined to 1.5 (CI = 08.3.0) for 10 or more years of use. Recency and timing of use did not explain the observed association. Among women aged 45 to 59, OC use was associated with little or no increase in risk: the RR estimate for three or more years of use was 1.3 (CI = 0.7-2.4). The findings add to the evidence from studies of White women and a recent study of Black women which have suggested an increased risk of breast cancer at young ages for moderate or long duration use of OCs.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D001741 Black or African American A person having origins in any of the black racial groups of Africa (https://www.federalregister.gov/documents/1997/10/30/97-28653/revisions-to-the-standards-for-the classification-of-federal-data-on-race-and-ethnicity). In the United States it is used for classification of federal government data on race and ethnicity. Race and ethnicity terms are self-identified social construct and may include terms outdated and offensive in MeSH to assist users who are interested in retrieving comprehensive search results for studies such as in longitudinal studies. African American,African Americans,African-American,Afro-American,Afro-Americans,Black Americans,Blacks,Negroes,African-Americans,Negro,Afro American,Afro Americans,American, African,American, Black,Black American
D001943 Breast Neoplasms Tumors or cancer of the human BREAST. Breast Cancer,Breast Tumors,Cancer of Breast,Breast Carcinoma,Cancer of the Breast,Human Mammary Carcinoma,Malignant Neoplasm of Breast,Malignant Tumor of Breast,Mammary Cancer,Mammary Carcinoma, Human,Mammary Neoplasm, Human,Mammary Neoplasms, Human,Neoplasms, Breast,Tumors, Breast,Breast Carcinomas,Breast Malignant Neoplasm,Breast Malignant Neoplasms,Breast Malignant Tumor,Breast Malignant Tumors,Breast Neoplasm,Breast Tumor,Cancer, Breast,Cancer, Mammary,Cancers, Mammary,Carcinoma, Breast,Carcinoma, Human Mammary,Carcinomas, Breast,Carcinomas, Human Mammary,Human Mammary Carcinomas,Human Mammary Neoplasm,Human Mammary Neoplasms,Mammary Cancers,Mammary Carcinomas, Human,Neoplasm, Breast,Neoplasm, Human Mammary,Neoplasms, Human Mammary,Tumor, Breast
D003276 Contraceptives, Oral Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both. Low-Dose Oral Contraceptive,Oral Contraceptive,Oral Contraceptives,Oral Contraceptives, Low-Dose,Oral Contraceptives, Phasic,Contraceptive, Low-Dose Oral,Contraceptive, Oral,Contraceptives, Low-Dose Oral,Contraceptives, Phasic Oral,Low Dose Oral Contraceptive,Low-Dose Oral Contraceptives,Oral Contraceptive, Low-Dose,Oral Contraceptives, Low Dose,Phasic Oral Contraceptives
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
September 1999, American journal of epidemiology,
J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
September 2017, Carcinogenesis,
J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
September 2001, Journal of the National Medical Association,
J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
January 2003, Cancer,
J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
February 1995, American journal of community psychology,
J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
June 2005, Cancer causes & control : CCC,
J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
February 2009, Qualitative health research,
J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
June 1984, MMWR. Morbidity and mortality weekly report,
J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
July 1996, American journal of epidemiology,
J R Palmer, and L Rosenberg, and R S Rao, and B L Strom, and M E Warshauer, and S Harlap, and A Zauber, and S Shapiro
January 2014, Asian Pacific journal of cancer prevention : APJCP,
Copied contents to your clipboard!