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Nineteen patients aged > 60 years with chronic hepatitis C (CHC) received interferon (IFN) therapy and a complete response (CR) was achieved by five of them (26%). The incidence of CH with severe fibrosis in this elderly group was significantly higher than in another 52 patients with CHC who were < 60 years of age (the younger group; P < 0.05). There was no significant difference in the hepatitis C virus (HCV) genotype distribution between the elderly group and the younger group. However, the HCV-RNA titre was significantly higher in the elderly group than in the younger group (P < 0.05). There was no significant difference in the efficacy rate of IFN in the elderly and younger groups after standardization of the background factors. In the elderly group, the HCV-RNA titre was significantly lower in the patients achieving CR than in those with no response (P < 0.05). These data suggest that elderly patients with a low HCV-RNA titre can still respond well to IFN therapy.
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
August 2000,
Hepatology (Baltimore, Md.),
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
May 2010,
Oncology letters,
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
July 2007,
Journal of gastroenterology and hepatology,
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
July 1955,
Journal of neurosurgery,
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
February 1989,
Transplantation,
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
August 2021,
Expert review of anti-infective therapy,
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
November 1965,
American journal of obstetrics and gynecology,
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
June 2007,
Hepatology (Baltimore, Md.),
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
June 2012,
Chinese medical journal,
N Horiike, and
T Masumoto, and
K Nakanishi, and
K Michitaka, and
K Kurose, and
I Ohkura, and
M Onji
July 1996,
Bailliere's clinical gastroenterology,
