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On the basis of sugar analysis and NMR spectroscopy, including selective spin-decoupling, one-dimensional NOE, two-dimensional homonuclear and 13C,1H-heteronuclear correlation spectroscopy, the following structure of the acidic O-specific polysaccharide of Proteus mirabilis O43 was established: -->4)-alpha-D-GalpA-(1-->3)-alpha-D-GalpA-(1-->3)-alpha-D-Gl cpNAc-(1-->4)-alpha - D-Glcp-(1-->, where GalA is galacturonic acid and Galp is galactopyranose. No serological cross-reactivity was observed between lipopolysaccharides of P. mirabilis O43 and other studied Proteus strains, except for P. mirabilis O10. The O-specific polysaccharide of P. mirabilis O43 was serologically active in precipitation and inhibition tests but the activity was lost after periodate oxidation. These data suggest that the O43 specificity is determined by a wide epitope with the immunodominant role of 4-substituted D-Glc or/and D-GalA, which are destroyed by periodate oxidation.
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
May 2003,
Carbohydrate research,
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
November 2008,
FEMS immunology and medical microbiology,
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
October 2005,
Carbohydrate research,
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
September 2003,
Carbohydrate research,
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
February 2023,
International journal of molecular sciences,
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
October 2015,
Carbohydrate research,
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
January 1978,
Archivum immunologiae et therapiae experimentalis,
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
January 1978,
Bulletin de l'Academie polonaise des sciences. Serie des sciences biologiques,
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
May 1996,
Biokhimiia (Moscow, Russia),
M Cedzyński, and
Y A Knirel, and
A Rózalski, and
A S Shashkov, and
E V Vinogradov, and
W Kaca
July 1947,
Journal of bacteriology,
