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In man, non emetic doses of apomorphine elicit a series of behavioural, neurological and psychological changes which are difficult to ascribe to the stimulation of postsynaptic dopamine receptors. Since similar effects are elicited by neuroleptic drugs, the functional changes induced by apomorphine in man might be interpreted as being the result of a decreased dopaminergic activity. The sedation and sleep, the improvement of choreic movements and the antipsychotic effect induced by non emetic doses of apomorphine are prevented by specific dopamine receptor blockers. These responses therefore are mediated through a stimulation of dopamine receptors leading to a decreased dopaminergic transmission. This new type of receptors might be identified with the so called "self-inhibitory" dopamine receptors.
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
January 1978,
Annali dell'Istituto superiore di sanita,
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
May 1974,
Pharmacology, biochemistry, and behavior,
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
January 1978,
Advances in biochemical psychopharmacology,
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
January 1976,
British journal of pharmacology,
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
November 1972,
The Journal of pharmacy and pharmacology,
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
January 1977,
Advances in biochemical psychopharmacology,
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
January 1983,
Psychopharmacology,
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
January 2013,
Frontiers in bioscience (Scholar edition),
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
June 1978,
European journal of pharmacology,
G U Corsini, and
M Del Zompo, and
M P Piccardi, and
A Mangoni, and
G L Gessa
January 1975,
Proceedings of the Western Pharmacology Society,
