Inhibition of mammary carcinogenesis in rats by sulfone metabolite of sulindac. 1995

H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
AMC Cancer Research Center, Denver, CO 80214, USA.

UI MeSH Term Description Entries
D008325 Mammary Neoplasms, Experimental Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS. Experimental Mammary Neoplasms,Neoplasms, Experimental Mammary,Experimental Mammary Neoplasm,Mammary Neoplasm, Experimental,Neoplasm, Experimental Mammary
D011451 Prostaglandin-Endoperoxide Synthases Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor. Fatty Acid Cyclo-Oxygenase,PGH Synthase,Prostaglandin H Synthase,Prostaglandin Synthase,Prostaglandin-Endoperoxide Synthase,Arachidonic Acid Cyclooxygenase,Cyclo-Oxygenase,Cyclooxygenase,Cyclooxygenases,Hydroperoxide Cyclase,PGH2 Synthetase,Prostaglandin Cyclo-Oxygenase,Prostaglandin Cyclooxygenase,Prostaglandin Endoperoxide Synthetase,Prostaglandin G-H Synthase,Prostaglandin H2 Synthetase,Prostaglandin Synthetase,Cyclase, Hydroperoxide,Cyclo Oxygenase,Cyclo-Oxygenase, Fatty Acid,Cyclo-Oxygenase, Prostaglandin,Cyclooxygenase, Arachidonic Acid,Cyclooxygenase, Prostaglandin,Endoperoxide Synthetase, Prostaglandin,Fatty Acid Cyclo Oxygenase,G-H Synthase, Prostaglandin,Prostaglandin Cyclo Oxygenase,Prostaglandin Endoperoxide Synthases,Prostaglandin G H Synthase,Synthase, PGH,Synthase, Prostaglandin,Synthase, Prostaglandin G-H,Synthase, Prostaglandin H,Synthase, Prostaglandin-Endoperoxide,Synthases, Prostaglandin-Endoperoxide,Synthetase, PGH2,Synthetase, Prostaglandin,Synthetase, Prostaglandin Endoperoxide,Synthetase, Prostaglandin H2
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000970 Antineoplastic Agents Substances that inhibit or prevent the proliferation of NEOPLASMS. Anticancer Agent,Antineoplastic,Antineoplastic Agent,Antineoplastic Drug,Antitumor Agent,Antitumor Drug,Cancer Chemotherapy Agent,Cancer Chemotherapy Drug,Anticancer Agents,Antineoplastic Drugs,Antineoplastics,Antitumor Agents,Antitumor Drugs,Cancer Chemotherapy Agents,Cancer Chemotherapy Drugs,Chemotherapeutic Anticancer Agents,Chemotherapeutic Anticancer Drug,Agent, Anticancer,Agent, Antineoplastic,Agent, Antitumor,Agent, Cancer Chemotherapy,Agents, Anticancer,Agents, Antineoplastic,Agents, Antitumor,Agents, Cancer Chemotherapy,Agents, Chemotherapeutic Anticancer,Chemotherapy Agent, Cancer,Chemotherapy Agents, Cancer,Chemotherapy Drug, Cancer,Chemotherapy Drugs, Cancer,Drug, Antineoplastic,Drug, Antitumor,Drug, Cancer Chemotherapy,Drug, Chemotherapeutic Anticancer,Drugs, Antineoplastic,Drugs, Antitumor,Drugs, Cancer Chemotherapy
D013467 Sulindac A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects. Aclin,Apo-Sulin,Arthrobid,Arthrocine,Chibret,Clinoril,Copal,Kenalin,Klinoril,MK-231,Novo-Sundac,Nu-Sulindac,Sulindal,Apo Sulin,MK 231,MK231,Novo Sundac,Nu Sulindac
D017207 Rats, Sprague-Dawley A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company. Holtzman Rat,Rats, Holtzman,Sprague-Dawley Rat,Rats, Sprague Dawley,Holtzman Rats,Rat, Holtzman,Rat, Sprague-Dawley,Sprague Dawley Rat,Sprague Dawley Rats,Sprague-Dawley Rats
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
January 1997, Cancer research,
H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
July 1997, Cancer research,
H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
June 1988, Cancer letters,
H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
January 1998, International journal of tissue reactions,
H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
February 2000, American journal of physiology. Gastrointestinal and liver physiology,
H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
July 1997, Journal of the National Cancer Institute,
H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
October 2006, Basic & clinical pharmacology & toxicology,
H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
January 1978, Archiv fur Geschwulstforschung,
H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
November 1989, Carcinogenesis,
H J Thompson, and S Briggs, and N S Paranka, and G A Piazza, and K Brendel, and P H Gross, and G J Sperl, and R Pamukcu, and D J Ahnen
January 1996, Journal of cellular biochemistry. Supplement,
Copied contents to your clipboard!