BIOMAT Database Logo BIOMAT Database Logo

[Anticonvulsants: pharmacokinetics, interactions, side effects and concomitant effects]. 1978

J Hirschmann

UI MeSH Term Description Entries
D010672 Phenytoin An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs. Diphenylhydantoin,Fenitoin,Phenhydan,5,5-Diphenylhydantoin,5,5-diphenylimidazolidine-2,4-dione,Antisacer,Difenin,Dihydan,Dilantin,Epamin,Epanutin,Hydantol,Phenytoin Sodium,Sodium Diphenylhydantoinate,Diphenylhydantoinate, Sodium
D004347 Drug Interactions The action of a drug that may affect the activity, metabolism, or toxicity of another drug. Drug Interaction,Interaction, Drug,Interactions, Drug
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

J Hirschmann
[Anticonvulsants and their side effects. II. Side effects].
September 1980, Kinderarztliche Praxis,
J Hirschmann
[Diphenylhydantoin. Metabolism, pharmacokinetics, interactions and side effects].
June 1976, Schweizerische medizinische Wochenschrift,
J Hirschmann
Cognitive side effects of anticonvulsants.
January 2001, The Journal of clinical psychiatry,
J Hirschmann
Decreasing side effects of anticonvulsants.
January 1986, Dimensions of critical care nursing : DCCN,
J Hirschmann
Letter: Immunological side-effects of anticonvulsants.
April 1976, Lancet (London, England),
J Hirschmann
Major system toxicities and side effects of anticonvulsants.
January 2001, The Journal of clinical psychiatry,
J Hirschmann
Pharmacokinetics of anticonvulsants.
December 1983, British journal of hospital medicine,
J Hirschmann
Pharmacokinetic interactions and side effects resulting from concomitant administration of lithium and divalproex sodium.
May 1996, The Journal of clinical psychiatry,
J Hirschmann
[Anticonvulsants. Therapeutic indications; secondary effects; drug interactions].
January 1987, Therapie,
J Hirschmann
Clinical pharmacokinetics of anticonvulsants.
January 1976, Clinical pharmacokinetics,
Copied contents to your clipboard!