-transparent.png){kind=logo}
Adrenal androgen hypersecretion either produced by genetic defects or reticular disfunction, is reduced by exogenous glucocorticoid administration and, as with any suppression therapy, it should relapse when the therapy is discontinued. However, prolonged remissions of adrenal androgen hypersecretion after discontinuing glucocorticoids have been described. We report 15 patients with adrenal hyperandrogenism and elevated levels of dehydroepiandrosterone sulfate that received treatment with dexamethasone. After one month of treatment with dexamethasone 0.5 mg/day, dehydroepiandrosterone sulfate levels returned to normal and remained so during a mean of 19 months receiving dexamethasone 0.25 mg/day. One year after discontinuing therapy, hormone levels continued within normal range in all patients. It is concluded that a long remission period of adrenal hyperandrogenism was achieves after discontinuing glucocorticoid therapy.
E Devoto, and
L Aravena, and
X Gaete
September 1990,
Bailliere's clinical obstetrics and gynaecology,
E Devoto, and
L Aravena, and
X Gaete
August 1991,
Wisconsin medical journal,
E Devoto, and
L Aravena, and
X Gaete
May 1991,
Presse medicale (Paris, France : 1983),
E Devoto, and
L Aravena, and
X Gaete
September 2017,
Clinical chemistry,
E Devoto, and
L Aravena, and
X Gaete
July 1973,
Klinicheskaia meditsina,
E Devoto, and
L Aravena, and
X Gaete
February 1947,
The American journal of medicine,
E Devoto, and
L Aravena, and
X Gaete
August 1964,
Deutsche medizinische Wochenschrift (1946),
E Devoto, and
L Aravena, and
X Gaete
November 1965,
Meditsinskaia radiologiia,
E Devoto, and
L Aravena, and
X Gaete
December 1970,
The Journal of pediatrics,
E Devoto, and
L Aravena, and
X Gaete
August 1997,
The Journal of rheumatology,
