-transparent.png){kind=logo}
Protection of mice from Mycobacterium avium infection by recombinant interleukin-12. 1995
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
First Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan.
Treatment with interleukin-12 (IL-12) significantly reduced the number of viable bacteria in mice infected with Mycobacterium avium. IL-12 itself, however, could not inhibit directly mycobacterial growth in vitro. IL-12 exerts antimycobacterial activity in vivo with a low level of toxicity, possibly by enhancing the host defense against the infection.
Related Publications
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
January 2005,
Immunobiology,
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
October 1995,
Infection and immunity,
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
June 1995,
The Journal of infectious diseases,
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
July 1999,
Immunology,
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
July 1988,
European journal of immunology,
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
December 2000,
Scandinavian journal of immunology,
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
June 1999,
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
June 1998,
Journal of immunology (Baltimore, Md. : 1950),
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
May 1991,
Infection and immunity,
K Kobayashi, and
T Kasama, and
J Yamazaki, and
M Hosaka, and
T Katsura, and
T Mochizuki, and
K Soejima, and
R M Nakamura
December 2002,
Journal of medical microbiology,
