Biomaterial Database

Time course of hypertrophic adaptations of the anterior latissimus dorsi muscle to stretch overload in aged Japanese quail. 1995

J A Carson, and S E Alway, and M Yamaguchi

Department of Exercise Science, Ohio State University, USA.

The purpose of this study was to determine if aged Japanese quail demonstrated an altered time course of change in the morphology of the anterior latissimus dorsi (ALD) muscle during the first two weeks of hypertrophy induced by stretch overload. The left wing of adult (12 weeks of age) and aged (90 weeks of age) birds were weighted with 10% of their body weight; the right wing served as the intra-animal control. Thirteen to sixteen birds from each age group were killed after 7 and 14 days of stretch overload. Total fiber number was quantified by counting all the fibers in a transverse section from the mid-belly of the ALD muscle. The aged ALD retained the ability to increase the mass and total fiber number of the stretched ALD after 7 (82%, 16%) and 14 (102%, 19%) days of stretch overload. However, there was a main effect of age on the capacity to increase muscle mass and total fiber number after stretch overload. These results suggest that aging diminishes the increase and alters the time course of adaptation in fiber number and myofibrillar mass of the stretch overloaded ALD during the first two weeks of stretch overload.

UI	MeSH Term	Description	Entries
D006984	Hypertrophy	General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).	Hypertrophies
D009119	Muscle Contraction	A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.	Inotropism,Muscular Contraction,Contraction, Muscle,Contraction, Muscular,Contractions, Muscle,Contractions, Muscular,Inotropisms,Muscle Contractions,Muscular Contractions
D009929	Organ Size	The measurement of an organ in volume, mass, or heaviness.	Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D003370	Coturnix	A genus of BIRDS in the family Phasianidae, order GALLIFORMES, containing the common European and other Old World QUAIL.	Japanese Quail,Coturnix japonica,Japanese Quails,Quail, Japanese,Quails, Japanese
D000222	Adaptation, Physiological	The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.	Adaptation, Physiologic,Adaptations, Physiologic,Adaptations, Physiological,Adaptive Plasticity,Phenotypic Plasticity,Physiological Adaptation,Physiologic Adaptation,Physiologic Adaptations,Physiological Adaptations,Plasticity, Adaptive,Plasticity, Phenotypic
D000375	Aging	The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.	Senescence,Aging, Biological,Biological Aging
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D014921	Wings, Animal	Movable feathered or membranous paired appendages by means of which certain animals such as birds, bats, or insects are able to fly.	Animal Wing,Animal Wings,Wing, Animal