-transparent.png){kind=logo}
Age-related changes of mRNA expression of amyloid precursor protein in the brain of senescence-accelerated mouse. 1995
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
Department of Pharmacology, College of Medicine, Seoul National University, Korea.
APP695 mRNA is only expressed in the brains of SAM. The expression of APP mRNA in SAM P1 mice brains is more marked than that in SAM R1 mice brain. APP mRNA expression was increased with advancing age in all brain regions of SAM P1 mice compared with SAM R1. Especially, the changes of the amount of APP mRNA in the prosencephalon and the mesencephalon are significant at P value of 0.05. We suggest that overexpression of APP mRNA may be related to accelerated aging phenomenon in the SAM brain. This is the first report of age-related increase in the amount of APP mRNA in the SAM brain.
Related Publications
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
December 2009,
Current aging science,
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
January 2009,
Experimental gerontology,
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
January 2001,
Biochemistry and cell biology = Biochimie et biologie cellulaire,
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
May 1993,
Nippon Ganka Gakkai zasshi,
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
February 1990,
Mechanisms of ageing and development,
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
August 1996,
Biochemical Society transactions,
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
October 1996,
Journal of periodontal research,
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
January 1994,
The Prostate,
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
March 1988,
The American journal of pathology,
H S Cho, and
S S Kim, and
W Choi, and
S H Kim, and
S J Jeong, and
Rhyna-Hong, and
Y H Chong, and
Y J Lee, and
C W Park, and
K W Lee
May 1997,
Neuroreport,
