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Effects of three different types of short-term applications (1-3 times during 1 week) of chlorhexidine (1 or 40%) on the susceptibility of 863 clinical isolates of Streptococcus mutans and 53 isolates of Streptococcus sobrinus from 58 subjects were studied. Chlorhexidine-resistant isolates were not found either before or after the treatment. The minimum inhibitory concentrations (MICs) to chlorhexidine of all isolates of S. mutans were < or = 1 microgram/ml, and of S. sobrinus < or = 2 micrograms/ml. S. mutans and S. sobrinus were also susceptible to ampicillin, penicillin, cefuroxime, and tetracycline. In conclusion, different short-term chlorhexidine regimens do not induce resistance in S. mutans or S. sobrinus and, furthermore, these species have so far retained their susceptibility to common antibiotics.
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
May 1993,
Antimicrobial agents and chemotherapy,
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
August 1976,
Antimicrobial agents and chemotherapy,
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
May 2006,
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology,
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
June 1991,
Oral microbiology and immunology,
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
January 1992,
Caries research,
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
March 2009,
Archives of oral biology,
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
January 1977,
Annales de microbiologie,
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
January 2002,
Caries research,
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
January 1990,
NCI monographs : a publication of the National Cancer Institute,
H Järvinen, and
K Pienihäkkinen, and
P Huovinen, and
J Tenovuo
May 1986,
Infection and immunity,
