Biomaterial Database

Sunscreen intolerance. Contact sensitization, photocontact sensitization, and irritancy of sunscreen agents. 1995

J O Funk, and S H Dromgoole, and H I Maibach

Department of Dermatology, Ludwig-Maximilians-University, Munich, Germany.

Reports of contact sensitization and photocontact sensitization induced by various sunscreening agents are reviewed. Current knowledge about the most often used sunscreening agents is summarized. The problems of cross-sensitization and sensitization in photodermatoses are discussed. Strategies for patch and photopatch testing, as well as immediate-type testing, are critically evaluated.

UI	MeSH Term	Description	Entries
D010129	4-Aminobenzoic Acid	An aminobenzoic acid isomer that combines with pteridine and GLUTAMIC ACID to form FOLIC ACID. The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in SUNSCREENS.	PABA,p-Aminobenzoic Acid,para-Aminobenzoic Acid,4-Aminobenzoic Acid, Potassium Salt,Aminobenzoic Acid (USP),Epit Vit,Epitelplast,Hachemina,Magnesium para-Aminobenzoate,Pabasan,Paraminan,Paraminol,Potaba,Potassium 4-Aminobenzoate,Potassium Aminobenzoate,4 Aminobenzoic Acid,4 Aminobenzoic Acid, Potassium Salt,4-Aminobenzoate, Potassium,Aminobenzoate, Potassium,Potassium 4 Aminobenzoate,p Aminobenzoic Acid,para Aminobenzoic Acid,para-Aminobenzoate, Magnesium
D010328	Patch Tests	Skin tests in which the sensitizer is applied to a patch of cotton cloth or gauze held in place for approximately 48-72 hours. It is used for the elicitation of a contact hypersensitivity reaction.	Patch Testing,Patch Test,Patch Testings,Test, Patch,Testing, Patch,Testings, Patch,Tests, Patch
D005079	Excipients	Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.	Excipient,Stabilizing Agent,Stabilizing Agents,Suspending Agent,Suspending Agents,Agent, Stabilizing,Agent, Suspending,Agents, Stabilizing,Agents, Suspending
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013473	Sunscreening Agents	Chemical or physical agents that protect the skin from sunburn and erythema by absorbing or blocking ultraviolet radiation.	Sunscreen,Sunscreens,Agents, Sunscreening
D017449	Dermatitis, Allergic Contact	A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.	Allergic Contact Dermatitis,Dermatitis, Allergic Eczematous,Dermatitis, Contact, Allergic,Allergic Contact Dermatitides,Allergic Eczematous Dermatitides,Allergic Eczematous Dermatitis,Contact Dermatitides, Allergic,Contact Dermatitis, Allergic,Dermatitides, Allergic Contact,Dermatitides, Allergic Eczematous,Eczematous Dermatitides, Allergic,Eczematous Dermatitis, Allergic
D017453	Dermatitis, Irritant	A non-allergic contact dermatitis caused by prolonged exposure to irritants and not explained by delayed hypersensitivity mechanisms.	Dermatitis, Primary Irritant,Irritant Dermatitis,Dermatitides, Irritant,Dermatitides, Primary Irritant,Irritant Dermatitides,Irritant Dermatitides, Primary,Irritant Dermatitis, Primary,Primary Irritant Dermatitides,Primary Irritant Dermatitis
D017454	Dermatitis, Photoallergic	A delayed hypersensitivity involving the reaction between sunlight or other radiant energy source and a chemical substance to which the individual has been previously exposed and sensitized. It manifests as a papulovesicular, eczematous, or exudative dermatitis occurring chiefly on the light-exposed areas of the skin.	Dermatitis, Contact, Photoallergic,Dermatitis, Contact, Photosensitive,Dermatitis, Photocontact,Photoallergy,Photoallergic Contact Dermatitis,Photosensitive Contact Dermatitis,Contact Dermatitides, Photoallergic,Contact Dermatitides, Photosensitive,Contact Dermatitis, Photoallergic,Contact Dermatitis, Photosensitive,Dermatitides, Photoallergic,Dermatitides, Photoallergic Contact,Dermatitides, Photocontact,Dermatitides, Photosensitive Contact,Dermatitis, Photoallergic Contact,Dermatitis, Photosensitive Contact,Photoallergic Contact Dermatitides,Photoallergic Dermatitides,Photoallergic Dermatitis,Photoallergies,Photocontact Dermatitides,Photocontact Dermatitis,Photosensitive Contact Dermatitides