We are reporting a young female who presented with a history of right flank pain and urinary tract infection off and on. On investigation, she was found to have a giant fork-shaped ureteral calculus in a bifid ureter. Since her ipsilateral renal unit was nonfunctioning, nephroureterectomy was performed. Such a case of giant staghorn ureteral calculus in a bifid ureter has never been reported in the world literature.