-transparent.png){kind=logo}
Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver have been investigated. After perfusing the lung to remove contaminating blood, this organ was found to have an apparent concentration of glutathione (2mM) which is approx. 20% of that found in the liver. Both organs contain very low levels of glutathione disulfide. Neither phenobarbital nor methylcholanthrene had a significant effect on the levels of reduced glutathione in lung and liver. In addition, the activities of some glutathione-metabolizing enzymes--glutathione reductase and glutathione S-transferase activity assayed with four different substrates--were observed to be 5-to 60-fold lower in lung tissue than in the liver.
M S Moron, and
J W Depierre, and
B Mannervik
February 1996,
Cancer letters,
M S Moron, and
J W Depierre, and
B Mannervik
February 1993,
Cancer letters,
M S Moron, and
J W Depierre, and
B Mannervik
October 1997,
Cancer letters,
M S Moron, and
J W Depierre, and
B Mannervik
January 1994,
Acta Europaea fertilitatis,
M S Moron, and
J W Depierre, and
B Mannervik
April 1983,
Biochemical pharmacology,
M S Moron, and
J W Depierre, and
B Mannervik
June 1981,
Xenobiotica; the fate of foreign compounds in biological systems,
M S Moron, and
J W Depierre, and
B Mannervik
August 1982,
Experientia,
M S Moron, and
J W Depierre, and
B Mannervik
June 1984,
Research communications in chemical pathology and pharmacology,
M S Moron, and
J W Depierre, and
B Mannervik
October 1985,
Cancer letters,
M S Moron, and
J W Depierre, and
B Mannervik
August 1984,
The American review of respiratory disease,
