[Determination of the alveolar dead space]. 1979

L A Sidorenko

The author suggests a method of finding the alveolar dead space (AIDS), i.e. the part of the functional dead space (FDS) which presents the greatest difficulties for determination. A1DS determination is based on the difference in the CO2 concentration in the venous blood flowing to the lungs for oxygenation under conditions of respiration at rest, and of CO2 concentration in the alveolar portions of expriation following 10-sex breath withholding at the level of the usual inspiration. The mean A1DS volume (VDA1) in % to the alveolar part of the tidal volume for 20 healthy persons in sitting position and in 12 of them in lying position was found: VDA1 (in sitting position)= = 8.0 +/- 1.5% (P = 0.95), sigma = 3%; VDA1 (in lying position) = = 5.0 +/- 0.7% (P = 0.95), sigma = 2.6%. It is suggested that FDS determined by this method be used to judge the efficacy of using the inspired air in the lung ventilation, to determine AIDS in the diagnosis of lung embolism, to judge the pulmonary circulation shunt by the difference between the value found according to Bohr's formula for FDS and the FDS value established according to the suggested formula.

UI MeSH Term Description Entries
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D011650 Pulmonary Alveoli Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place. Alveoli, Pulmonary,Alveolus, Pulmonary,Pulmonary Alveolus
D012126 Respiratory Dead Space That part of the RESPIRATORY TRACT or the air within the respiratory tract that does not exchange OXYGEN and CARBON DIOXIDE with pulmonary capillary blood. Dead Space, Respiratory,Dead Spaces, Respiratory,Respiratory Dead Spaces,Space, Respiratory Dead,Spaces, Respiratory Dead
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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