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Conditioned medium from a cell strain derived from a patient with mastocytosis induces the development of mature human mast cells in vitro from normal human bone marrow. 1995
L Li, and
J J Macpherson, and
S Adelstein, and
C L Bunn, and
K Atkinson, and
K Phadke, and
S A Krilis
Department of Immunology, Allergy and Infectious Disease, St. George Hospital, Kogarah, Australia.
Mature human mast cells were obtained from human bone marrow in a coculture system using conditioned medium from a human mastocytosis cell strain. These cells expressed the high-affinity IgE receptor and were tryptase, chymase and carboxypeptidase positive.
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