Biomaterial Database

Peroxisomal enzyme activity changes in the tail of anuran tadpoles during metamorphosis. 1995

A Kashiwagi

Laboratory for Amphibian Biology, Faculty of Science, Hiroshima University, Japan.

This study attempts to clarify peroxisomal enzyme activity changes in the atrophying tail of anuran tadpoles. Changes in catalase, D-amino acid oxidase and urate oxidase activity were spectrophotometrically investigated using tadpole tails of Rana japonica and Rana nigromaculata. In R. japonica, total catalase activity decreased in tails undergoing regression during spontaneous and DL-thyroxine (T4)-induced metamorphosis, whereas total D-amino acid oxidase and urate oxidase activity increased. In R. nigromaculata, total activity of catalase decreased in tails regressing spontaneously. Total D-amino acid oxidase activity increased during advanced stages of tail regression, but total urate oxidase activity decreased. Specific activity of tadpole peroxisomal enzymes in the above two species was found to be highest for D-amino acid oxidase, followed by urate oxidase and then catalase at latter stages of normal tail regression. Atrophying tadpole tails develop a mechanism for hydrogen peroxide production, which may contribute to cell death in this organ.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008675	Metamorphosis, Biological	Profound physical changes during maturation of living organisms from the immature forms to the adult forms, such as from TADPOLES to frogs; caterpillars to BUTTERFLIES.	Biological Metamorphosis,Biological Metamorphoses,Metamorphoses, Biological
D008830	Microbodies	Electron-dense cytoplasmic particles bounded by a single membrane, such as PEROXISOMES; GLYOXYSOMES; and glycosomes.	Glycosomes,Glycosome,Microbody
D009929	Organ Size	The measurement of an organ in volume, mass, or heaviness.	Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011506	Proteins	Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.	Gene Products, Protein,Gene Proteins,Protein,Protein Gene Products,Proteins, Gene
D002374	Catalase	An oxidoreductase that catalyzes the conversion of HYDROGEN PEROXIDE to water and oxygen. It is present in many animal cells. A deficiency of this enzyme results in ACATALASIA.	Catalase A,Catalase T,Manganese Catalase,Mn Catalase
D005260	Female		Females
D000594	Amino Acid Oxidoreductases	A class of enzymes that catalyze oxidation-reduction reactions of amino acids.	Acid Oxidoreductases, Amino,Oxidoreductases, Amino Acid
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia