Case histories of 510 patients operated on for chronic destructive pulmonary tuberculosis and mycetoma are analyzed, as are the findings of examinations of 56 patients with cavitary forms of lung involvement (mostly cavernous and fibrocavernous tuberculosis), whose resected lung and bronchial specimens were inoculated to detect the fungi. X-Ray and tomographic examinations were carried out according to the routine methods. Blood serum IgG antibodies to aspergillosis antigen were determined in the enzyme immunoassay. The pathologic material (sputum, bronchial lavage water) was studied in tissue cultures and the pathomorphologic findings analyzed. An x-ray symptom of the foamy nuclear (septal) structure of pulmonary shifts was revealed, that represents a sort of a pathologic tissue response in one of bronchopulmonary aspergillosis forms. This condition was confirmed by high (over 1:1600) values of enzyme immunoassay with aspergillosis antigen.