BIOMAT Database Logo BIOMAT Database Logo

New variant of TEM-10 beta-lactamase gene produced by a clinical isolate of proteus mirabilis. 1995

T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
Department of Microbiology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.

A clinical isolate of Proteus mirabilis was found to produce a new variant of the TEM-10 beta-lactamase gene. This is the first report of TEM-10 production by P. mirabilis and the first report of extended-spectrum beta-lactamase production by an isolate of this species recovered in the United States.

UI MeSH Term Description Entries
D008826 Microbial Sensitivity Tests Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses). Bacterial Sensitivity Tests,Drug Sensitivity Assay, Microbial,Minimum Inhibitory Concentration,Antibacterial Susceptibility Breakpoint Determination,Antibiogram,Antimicrobial Susceptibility Breakpoint Determination,Bacterial Sensitivity Test,Breakpoint Determination, Antibacterial Susceptibility,Breakpoint Determination, Antimicrobial Susceptibility,Fungal Drug Sensitivity Tests,Fungus Drug Sensitivity Tests,Sensitivity Test, Bacterial,Sensitivity Tests, Bacterial,Test, Bacterial Sensitivity,Tests, Bacterial Sensitivity,Viral Drug Sensitivity Tests,Virus Drug Sensitivity Tests,Antibiograms,Concentration, Minimum Inhibitory,Concentrations, Minimum Inhibitory,Inhibitory Concentration, Minimum,Inhibitory Concentrations, Minimum,Microbial Sensitivity Test,Minimum Inhibitory Concentrations,Sensitivity Test, Microbial,Sensitivity Tests, Microbial,Test, Microbial Sensitivity,Tests, Microbial Sensitivity
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D008969 Molecular Sequence Data Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. Sequence Data, Molecular,Molecular Sequencing Data,Data, Molecular Sequence,Data, Molecular Sequencing,Sequencing Data, Molecular
D011512 Proteus Infections Infections with bacteria of the genus PROTEUS. Infections, Proteus,Infection, Proteus,Proteus Infection
D011513 Proteus mirabilis A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that is frequently isolated from clinical specimens. Its most common site of infection is the urinary tract.
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001483 Base Sequence The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence. DNA Sequence,Nucleotide Sequence,RNA Sequence,DNA Sequences,Base Sequences,Nucleotide Sequences,RNA Sequences,Sequence, Base,Sequence, DNA,Sequence, Nucleotide,Sequence, RNA,Sequences, Base,Sequences, DNA,Sequences, Nucleotide,Sequences, RNA
D001618 beta-Lactamases Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins. beta-Lactamase,beta Lactamase,beta Lactamases
D016133 Polymerase Chain Reaction In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships. Anchored PCR,Inverse PCR,Nested PCR,PCR,Anchored Polymerase Chain Reaction,Inverse Polymerase Chain Reaction,Nested Polymerase Chain Reaction,PCR, Anchored,PCR, Inverse,PCR, Nested,Polymerase Chain Reactions,Reaction, Polymerase Chain,Reactions, Polymerase Chain

Related Publications

T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
TEM-89 beta-lactamase produced by a Proteus mirabilis clinical isolate: new complex mutant (CMT 3) with mutations in both TEM-59 (IRT-17) and TEM-3.
December 2001, Antimicrobial agents and chemotherapy,
T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
New TEM variant (TEM-92) produced by Proteus mirabilis and Providencia stuartii isolates.
April 2001, Antimicrobial agents and chemotherapy,
T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
Chromosomally encoded ampC-type beta-lactamase in a clinical isolate of Proteus mirabilis.
May 1998, Antimicrobial agents and chemotherapy,
T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
TEM-103/IRT-28 beta-lactamase, a new TEM variant produced by Escherichia coli BM4511.
November 2002, Antimicrobial agents and chemotherapy,
T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
Integron-located VEB-1 extended-spectrum beta-lactamase gene in a Proteus mirabilis clinical isolate from Vietnam.
November 2000, The Journal of antimicrobial chemotherapy,
T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
Characterization of TEM-56, a novel beta-lactamase produced by a Klebsiella pneumoniae clinical isolate.
February 2000, Antimicrobial agents and chemotherapy,
T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
Catalytic and structural properties of IRT-21 beta-lactamase (TEM-77) from a co-amoxiclav-resistant Proteus mirabilis isolate.
December 2001, FEMS microbiology letters,
T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
Characterization of an inhibitor-resistant enzyme IRT-2 derived from TEM-2 beta-lactamase produced by Proteus mirabilis strains.
August 1996, The Journal of antimicrobial chemotherapy,
T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
Biochemical analysis of TEM-134, a new TEM-type extended-spectrum beta-lactamase variant produced in a Citrobacter koseri clinical isolate from an Italian hospital.
October 2007, The Journal of antimicrobial chemotherapy,
T Palzkill, and K S Thomson, and C C Sanders, and E S Moland, and W Huang, and T W Milligan
TEM-72, a new extended-spectrum beta-lactamase detected in Proteus mirabilis and Morganella morganii in Italy.
September 2000, Antimicrobial agents and chemotherapy,
Copied contents to your clipboard!