Biomaterial Database

Influence of hydration state on plasma volume changes during ultrafiltration. 1995

V Wizemann, and A Leibinger, and K Mueller, and A Nilson

Georg Haas Dialysis Center, Giessen, Germany.

To assess the influence of hydration state on plasma volume (PV) changes during ultrafiltration, 11 clinically normhydrated patients on maintenance hemodialysis were studied intraindividually during 2 hydration states differing by 2-15% of lean body mass (LBM). Plasma volume was measured continually during a 15-min ultrafiltration test including an ultrafiltration of 1% of target weight and during a 45-min follow-up period of blood recirculation through the dialyzer without ultrafiltration. In all patients a maximal decrease in relative PV was more pronounced when there was less hydration and when the grade of hydration correlated inversely with the maximal response of PV decrease (r = -0.68, p < 0.001). The same was observed between the hydration state and the slope of the PV decrease (r = -0.69, p < 0.001). Plasma refilling was estimated in the period following ultrafiltration. The slope of the plasma volume increase correlated with the grade of hydration (r = 0.31, p < 0.05) as did the asymtote of PV (r = 0.4, p < 0.01). It is concluded that the less hydrated a dialysis patient is, the more pronounced will be the fall of the ultrafiltration-induced plasma volume and the less distinct will be the recovery of the plasma volume after the discontinuation of ultrafiltration.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010953	Plasma Volume	Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.	Blood Plasma Volume,Blood Plasma Volumes,Plasma Volumes,Volume, Blood Plasma,Volume, Plasma,Volumes, Blood Plasma,Volumes, Plasma
D001824	Body Constitution	The physical characteristics of the body, including the mode of performance of functions, the activity of metabolic processes, the manner and degree of reactions to stimuli, and power of resistance to the attack of pathogenic organisms.	Body Constitutions,Constitution, Body,Constitutions, Body
D001834	Body Water	Fluids composed mainly of water found within the body.	Water, Body
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D005260	Female		Females
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006435	Renal Dialysis	Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.	Dialysis, Extracorporeal,Dialysis, Renal,Extracorporeal Dialysis,Hemodialysis,Dialyses, Extracorporeal,Dialyses, Renal,Extracorporeal Dialyses,Hemodialyses,Renal Dialyses
D006440	Hemofiltration	Extracorporeal ULTRAFILTRATION technique without HEMODIALYSIS for treatment of fluid overload and electrolyte disturbances affecting renal, cardiac, or pulmonary function.	Arteriovenous Hemofiltration,Venovenous Hemofiltration,Arteriovenous Hemofiltrations,Hemofiltration, Arteriovenous,Hemofiltration, Venovenous,Hemofiltrations,Venovenous Hemofiltrations