Biomaterial Database

Addiction severity, psychopathology and treatment compliance in cocaine-dependent mothers. 1995

T K Killeen, and K T Brady, and A Thevos

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425-0742, USA.

A retrospective chart review of clinical assessments encompassing psychiatric diagnosis, addiction severity and psychosocial functioning of cocaine-dependent pregnant or postpartum women during inpatient treatment was obtained. Predictive value of the elements of the assessment battery on aftercare compliance was determined. METHODS The charts of forty-one cocaine-dependent pregnant or postpartum women treated for substance abuse were reviewed for addiction severity and aftercare compliance. Thirty of these patients were administered the Structured Clinical Interview for DSM-III-R (SCID I and II) and screened for history of victimization during inpatient treatment. All women were divided into two groups, aftercare treatment compliers (TCs) and aftercare treatment noncompliers (TNCs). TCs were those patients who attended at least one-half of the aftercare sessions. RESULTS TCs had significantly lower scores on the psychiatric (p < or = .05) and employment (p < or = .01) subscales of the ASI, indicating lesser problem severity. The total composite mean ASI score, although not statistically significant, was also lower for TCs. Of the thirty subjects that were administered the SCID-I and II, sixty-seven percent had an Axis I disorder. TNCs were significantly more likely to have an anxiety disorder (p < or = 0.05). Eighty percent of subjects had at least one Axis II disorder. TNCs were also significantly more likely to have any Axis II disorder (p < or = 0.05), and to have Cluster B and Cluster C personality disorders (p < or = 0.05). In addition, seventy-three percent of subjects reported victimization, with TNCs significantly more likely (p < or = 0.05) to have experienced childhood abuse. CONCLUSIONS In this sample of pregnant cocaine using women, the majority of women had current Axis I and II disorders as well as history of victimization. The results suggest that the ASI employment and psychiatric subscales may be predictive of aftercare compliance. The presence of certain Axis I and/or Axis II disorders also appear to be predictors of poor compliance. Treatment of pregnant substance using women must be designed to address issues of victimization as well as psychiatric disorders.

UI	MeSH Term	Description	Entries
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D009035	Mothers	Female parents, human or animal.	Mothers' Clubs,Club, Mothers',Clubs, Mothers',Mother,Mother Clubs,Mother's Clubs,Mothers Clubs,Mothers' Club
D010349	Patient Compliance	Voluntary cooperation of the patient in following a prescribed regimen.	Client Adherence,Client Compliance,Non-Adherent Patient,Patient Adherence,Patient Cooperation,Patient Noncompliance,Patient Non-Adherence,Patient Non-Compliance,Patient Nonadherence,Therapeutic Compliance,Treatment Compliance,Adherence, Client,Adherence, Patient,Client Compliances,Compliance, Client,Compliance, Patient,Compliance, Therapeutic,Compliance, Treatment,Cooperation, Patient,Non Adherent Patient,Non-Adherence, Patient,Non-Adherent Patients,Non-Compliance, Patient,Nonadherence, Patient,Noncompliance, Patient,Patient Non Adherence,Patient Non Compliance,Patient, Non-Adherent,Therapeutic Compliances,Treatment Compliances
D010554	Personality Disorders	A major deviation from normal patterns of behavior.	Avoidant Personality Disorder,Impulse-Ridden Personality,Inadequate Personality,Avoidant Personality Disorders,Impulse Ridden Personality,Personality Disorder,Personality Disorder, Avoidant,Personality Disorders, Avoidant,Personality, Impulse-Ridden,Personality, Inadequate
D010555	Personality Inventory	Check list, usually to be filled out by a person about himself, consisting of many statements about personal characteristics which the subject checks.	Edwards Personal Preference Schedule,Myers-Briggs Type Indicator,Indicator, Myers-Briggs Type,Inventories, Personality,Inventory, Personality,Myers Briggs Type Indicator,Personality Inventories
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011248	Pregnancy Complications	Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.	Adverse Birth Outcomes,Complications, Pregnancy,Adverse Birth Outcome,Birth Outcome, Adverse,Complication, Pregnancy,Outcome, Adverse Birth,Pregnancy Complication
D011644	Puerperal Disorders	Disorders or diseases associated with PUERPERIUM, the six-to-eight-week period immediately after PARTURITION in humans.	Disorder, Puerperal,Disorders, Puerperal,Puerperal Disorder
D003042	Cocaine	An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.	Cocaine HCl,Cocaine Hydrochloride,HCl, Cocaine,Hydrochloride, Cocaine
D005260	Female		Females