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Radiation therapy has been widely used for palliative management of inoperable metastatic malignant melanoma. For patients with nodal disease, response rates of approximately 70% have been reported. There are limited data concerning the role of adjuvant irradiation following therapeutic lymph node dissection. In this review, 57 patients with isolated resectable and nonresectable nodal disease have been treated with radiation. The overall response rate is 84% for bulky disease. Large fractions are beneficial. The median disease-free survivals were 11 months after adjuvant treatment and 7 months for those with inoperable disease. The median overall survivals were 20 months and 18 months, respectively. Local control in long-term survivors was excellent. Sixty-five percent of patients developed distant metastases. There is a need for additional studies with the use of adjuvant radiation therapy following lymph node dissection.
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
July 1999,
International journal of radiation oncology, biology, physics,
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
April 2003,
The Surgical clinics of North America,
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
December 1996,
The Surgical clinics of North America,
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
November 1978,
Cancer,
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
May 1998,
Ophthalmic surgery and lasers,
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
December 1979,
Missouri medicine,
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
February 1952,
The American journal of roentgenology, radium therapy, and nuclear medicine,
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
November 1973,
Rinsho hoshasen. Clinical radiography,
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
October 2002,
Dermatologic clinics,
B H Burmeister, and
B M Smithers, and
M Poulsen, and
G R McLeod, and
G Bryant, and
L Tripcony, and
C Thorpe
April 1981,
Lakartidningen,
