-transparent.png){kind=logo}
Protein synthesis was recorded in NHIK 3025 cells when cultured either during extremely hypoxic conditions or following reoxygenation. The rate of total protein synthesis in NHIK 3025 cells was found to be reduced to 30-40% of the rate in control cells within 1 h after the start of hypoxia. After reoxygenation, the rate of total protein synthesis was found to increase rapidly back to the control level. To reveal the stage of regulation of hypoxia associated proteins (HAP), mRNA was isolated from NHIK 3025 cells and translated in an in vitro translation kit. The results indicated that the relative amount of mRNA, of at least two HAP (80 and 45 kD), was increased under extremely hypoxic conditions ([O2] < 4ppm). This implies that some HAP are regulated pre-translationally.
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
April 1993,
The American journal of physiology,
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
December 1995,
The American journal of physiology,
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
November 1987,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
February 1965,
Cancer research,
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
September 1986,
Cancer research,
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
December 1982,
Experimental cell research,
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
January 2005,
FEBS letters,
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
January 1993,
Cell proliferation,
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
January 2018,
Anti-cancer agents in medicinal chemistry,
S M Kraggerud, and
J A Sandvik, and
E O Pettersen
June 1999,
Biochimica et biophysica acta,
