False-positive cryptococcal antigen latex agglutination caused by disinfectants and soaps. 1995

L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
Microbiology Department, Associated Regional and University Pathologists, Inc., Salt Lake City, UT 84108, USA.

Five disinfectants or soaps were tested to determine if any could be responsible for false-positive results obtained with the Latex-Crypto Antigen Detection System kit (Immuno-Mycologics, Inc., Norman, Okla.). Three disinfectants or soaps (Derma soap, 7X, and Bacdown) produced false-positive agglutination after repeated washing of ring slides during testing of a known negative cerebrospinal fluid specimen.

UI MeSH Term Description Entries
D007841 Latex Fixation Tests Passive agglutination tests in which antigen is adsorbed onto latex particles which then clump in the presence of antibody specific for the adsorbed antigen. (From Stedman, 26th ed) Latex Agglutination Tests,Agglutination Test, Latex,Agglutination Tests, Latex,Fixation Test, Latex,Fixation Tests, Latex,Latex Agglutination Test,Latex Fixation Test,Test, Latex Agglutination,Test, Latex Fixation,Tests, Latex Agglutination,Tests, Latex Fixation
D003453 Cryptococcosis Fungal infection caused by genus CRYPTOCOCCUS. C gattii Infection,C neoformans Infection,C. gattii Infection,C. neoformans Infection,Cryptococcus Infection,Cryptococcus Infections,Cryptococcus gattii Infection,Torulosis,Cryptococcus neoformans Infection,C gattii Infections,C neoformans Infections,C. gattii Infections,C. neoformans Infections,Cryptococcoses,Cryptococcus gattii Infections,Cryptococcus neoformans Infections,Infection, C gattii,Infection, C neoformans,Infection, C. gattii,Infection, C. neoformans,Infection, Cryptococcus,Infection, Cryptococcus gattii,Infection, Cryptococcus neoformans,Infections, C gattii,Infections, C. neoformans,Toruloses
D003455 Cryptococcus neoformans A species of the fungus CRYPTOCOCCUS. Its teleomorph is Filobasidiella neoformans. Blastomyces neoformans,Debaryomyces neoformans,Filobasidiella neoformans,Lipomyces neoformans,Saccharomyces neoformans,Torula neoformans,Torulopsis neoformans,Cryptococcus neoformans var. grubii
D004202 Disinfectants Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed) Biocide,Disinfectant,Biocides
D005189 False Positive Reactions Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed) False Positive Reaction,Positive Reaction, False,Positive Reactions, False,Reaction, False Positive,Reactions, False Positive
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000946 Antigens, Fungal Substances of fungal origin that have antigenic activity. Fungal Antigen,Fungal Antigens,Antigen, Fungal
D012915 Soaps Sodium or potassium salts of long chain fatty acids. These detergent substances are obtained by boiling natural oils or fats with caustic alkali. Sodium soaps are harder and are used as topical anti-infectives and vehicles in pills and liniments; potassium soaps are soft, used as vehicles for ointments and also as topical antimicrobials. Soap Solution,Soap,Soap Solutions,Solution, Soap,Solutions, Soap

Related Publications

L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
November 1985, Journal of clinical microbiology,
L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
February 2002, European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology,
L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
February 1985, Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
April 1988, Clinical chemistry,
L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
September 1993, Journal of clinical microbiology,
L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
April 1986, Annals of neurology,
L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
February 1982, Journal of clinical pathology,
L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
July 1987, The American journal of medicine,
L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
September 1994, Journal of clinical microbiology,
L B Blevins, and J Fenn, and H Segal, and P Newcomb-Gayman, and K C Carroll
June 1990, Lancet (London, England),
Copied contents to your clipboard!