Electrocardiographic abnormalities in patients with Cushing's syndrome. 1995

K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
First Department of Internal Medicine, Oita Medical University, Japan.

The electrocardiograms in 8 patients with Cushing's syndrome and 4 with Cushing's disease were studied. The patients were divided into group A with electrocardiographic abnormalities and group B without. The mean age was significantly higher in group B than in group A. However, blood pressure, mean heart rate and the plasma adrenocorticotropic hormone level showed no significant differences between the two groups. In group A, the plasma concentration of cortisol had a tendency to be higher than in group B (A vs. B: 281 +/- 100 ng/ml, 188 +/- 9 ng/ml, respectively). Echocardiography performed on three of four patients in group A revealed cardiac hypertrophy. While, in group B, echocardiography performed on two patients showed no hypertrophic findings. As a result, it seems that the electrocardiographic changes are correlated with the plasma level of cortisol via myocardial hypertrophy.

UI MeSH Term Description Entries
D006973 Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D003480 Cushing Syndrome A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent. Cushing's Syndrome,Hypercortisolism,Syndrome, Cushing,Syndrome, Cushing's
D004452 Echocardiography Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic. Echocardiography, Contrast,Echocardiography, Cross-Sectional,Echocardiography, M-Mode,Echocardiography, Transthoracic,Echocardiography, Two-Dimensional,Transthoracic Echocardiography,2-D Echocardiography,2D Echocardiography,Contrast Echocardiography,Cross-Sectional Echocardiography,Echocardiography, 2-D,Echocardiography, 2D,M-Mode Echocardiography,Two-Dimensional Echocardiography,2 D Echocardiography,Cross Sectional Echocardiography,Echocardiography, 2 D,Echocardiography, Cross Sectional,Echocardiography, M Mode,Echocardiography, Two Dimensional,M Mode Echocardiography,Two Dimensional Echocardiography
D004562 Electrocardiography Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY. 12-Lead ECG,12-Lead EKG,12-Lead Electrocardiography,Cardiography,ECG,EKG,Electrocardiogram,Electrocardiograph,12 Lead ECG,12 Lead EKG,12 Lead Electrocardiography,12-Lead ECGs,12-Lead EKGs,12-Lead Electrocardiographies,Cardiographies,ECG, 12-Lead,EKG, 12-Lead,Electrocardiograms,Electrocardiographies, 12-Lead,Electrocardiographs,Electrocardiography, 12-Lead
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006854 Hydrocortisone The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions. Cortef,Cortisol,Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-,11-Epicortisol,Cortifair,Cortril,Epicortisol,Hydrocortisone, (11 alpha)-Isomer,Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer,11 Epicortisol
D000324 Adrenocorticotropic Hormone An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP). ACTH,Adrenocorticotropin,Corticotropin,1-39 ACTH,ACTH (1-39),Adrenocorticotrophic Hormone,Corticotrophin,Corticotrophin (1-39),Corticotropin (1-39),Hormone, Adrenocorticotrophic,Hormone, Adrenocorticotropic

Related Publications

K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
May 1992, Clinical endocrinology,
K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
October 2018, JAMA cardiology,
K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
October 2018, JAMA cardiology,
K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
January 2024, Heart failure reviews,
K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
May 2024, Scientific reports,
K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
August 2018, Current opinion in endocrinology, diabetes, and obesity,
K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
September 1986, Research in veterinary science,
K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
October 2014, Metabolic syndrome and related disorders,
K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
January 1968, Problemy endokrinologii,
K Tsuda, and T Saikawa, and H Yonemochi, and T Maeda, and N Shimoyama, and M Hara, and Y Ito, and T Sakata
July 1990, The Western journal of medicine,
Copied contents to your clipboard!