[Aspergillosis of the larynx]. 1995

H Nong, and J Li, and G Huang
First Affiliated Hospital, Guangxi Medical University, Nanning.

Aspergillosis of the larynx is extremely rare. Six cases of aspergillosis of the larynx were presented. Clinical characters of the patients were as follows: (1) their physical conditions were excellent: (2) Hoarsenes was the first symptom; (3) true vocal cord demonstrated white mass; (4) Biopsy of the lesion revealed suppurative, granulomatous and necrotic inflammation with hyphae and spore with in the tissue; (5) Culture of fungi displayed tobaco colour colonies of aspergillus. microscopic examination demonstrated spore and septate hyphae with coral-shape dichotomous banching and flask-shape vesicle with phialide and spore on top; (6) All patients were cured with Ketoconazol and Itraconazol without recurrence for long-term follow-up. Etiology, diagnosis and therapy of aspergillosis of the larynx were discussed.

UI MeSH Term Description Entries
D007654 Ketoconazole Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients. Nizoral,R-41400,R41,400,R41400,R 41400
D007818 Laryngeal Diseases Pathological processes involving any part of the LARYNX which coordinates many functions such as voice production, breathing, swallowing, and coughing. Laryngeal Perichondritis,Larynx Diseases,Disease, Laryngeal,Disease, Larynx,Diseases, Laryngeal,Diseases, Larynx,Laryngeal Disease,Laryngeal Perichondritides,Larynx Disease,Perichondritides, Laryngeal,Perichondritis, Laryngeal
D008297 Male Males
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001228 Aspergillosis Infections with fungi of the genus ASPERGILLUS. Aspergillus Infection,Aspergilloses,Aspergillus Infections,Infection, Aspergillus,Infections, Aspergillus
D001232 Aspergillus fumigatus A species of imperfect fungi from which the antibiotic fumigatin is obtained. Its spores may cause respiratory infection in birds and mammals. Aspergillus fumigates,Neosartorya fumigata,Sartorya fumigata
D017964 Itraconazole A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis. Orungal,R-51211,Sporanox,R 51211,R51211

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