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A strain carrying the ilv0603 mutation has been isolated in E. coli K-12 and its characteristics were found to be very similar to those previously reported by Ramakrishnan and Adelberg (1965a) for other ilv0 mutants. The strain carrying the ilv0603 mutation is resistant to valine inhibition (Valr) and we show that this resistance depends on the expression of a newly recognized gene, ilvG, which is located at min 75, between ilvE and ilvD on the E. coli K-12 map. The ilvG gene causes the expression of a Valr acetolactate synthase, which is detectable only when the ilv0603 mutation is also present in cis on the same chromosome. Under these conditions the Valr acetolactate synthase activity is eluted, on a hydroxylapatite column, at an ionic strength slightly lower than that required for elution of the remaining acetolactate synthase activity (sensitive to valine inhibition). The Valr peak is missing in a strain carrying an ilvG (amber) mutation.
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
October 1974,
Journal of bacteriology,
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
November 1977,
Molecular & general genetics : MGG,
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
December 1974,
Journal of bacteriology,
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
July 1985,
Genetika,
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
January 1993,
Biochimie,
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
March 1979,
Molecular & general genetics : MGG,
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
June 1989,
Proceedings of the National Academy of Sciences of the United States of America,
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
June 1969,
Journal of bacteriology,
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
October 1966,
Canadian journal of biochemistry,
R Favre, and
A Wiater, and
S Puppo, and
M Iaccarino
November 1974,
Journal of bacteriology,
