BIOMAT Database Logo BIOMAT Database Logo

Bactericidal activity of normal human serum against Morganella, Proteus, and Providencia strains. 1995

U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
Department of Microbiology, Medical Academy, Wrocław, Poland.

The susceptibility od Proteus, Providencia, and Morganella strains to bactericidal action of human serum was examined. The percentage of survival was determined after one and three hours incubation with 50% human serum. The susceptible strains were treated by serum preparations with blocked classical or alternative complement activation pathways as well as with lysozyme removed. Following mechanisms of the bactericidal action of serum were found: complement activated by the classical or alternative pathway with participation of lysozyme, complement activated simultaneously via both pathways-while the participation of lysozyme was necessary for killing some strains and superfluos for others and complement activated only via the classical pathway without lysozyme.

UI MeSH Term Description Entries
D009113 Muramidase A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC 3.2.1.17. Lysozyme,Leftose,N-Acetylmuramide Glycanhydrolase,Glycanhydrolase, N-Acetylmuramide,N Acetylmuramide Glycanhydrolase
D011511 Proteus A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in the intestines of humans and a wide variety of animals, as well as in manure, soil, and polluted waters. Its species are pathogenic, causing urinary tract infections and are also considered secondary invaders, causing septic lesions at other sites of the body.
D011532 Providencia Gram-negative rods isolated from human urine and feces.
D001770 Blood Bactericidal Activity The natural bactericidal property of BLOOD due to normally occurring antibacterial substances such as beta lysin, leukin, etc. This activity needs to be distinguished from the bactericidal activity contained in a patient's serum as a result of antimicrobial therapy, which is measured by a SERUM BACTERICIDAL TEST. Activities, Blood Bactericidal,Activity, Blood Bactericidal,Bactericidal Activities, Blood,Bactericidal Activity, Blood,Blood Bactericidal Activities
D003167 Complement Activation The sequential activation of serum COMPLEMENT PROTEINS to create the COMPLEMENT MEMBRANE ATTACK COMPLEX. Factors initiating complement activation include ANTIGEN-ANTIBODY COMPLEXES, microbial ANTIGENS, or cell surface POLYSACCHARIDES. Activation, Complement,Activations, Complement,Complement Activations
D004755 Enterobacteriaceae A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock. Coliform Bacilli,Enterobacteria,Ewingella,Leclercia,Paracolobactrum,Sodalis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
[Susceptibility of Proteus, Morganella and Providencia strains isolated from patients with urinary tract infections on bactericidal activity of normal human serum].
January 1993, Medycyna doswiadczalna i mikrobiologia,
U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
[Bactericidal activity and capacity for selection of mutants resistant to imipenmen and meropenem in strains of Proteus, Morganella and Providencia].
January 1998, Enfermedades infecciosas y microbiologia clinica,
U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
Haemagglutinins and fimbriae of Morganella, Proteus and Providencia.
November 1982, Journal of medical microbiology,
U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
Innate human serum bactericidal activity against Salmonella, Shigella, Citrobacter and Providencia sp.
January 1982, Methods and findings in experimental and clinical pharmacology,
U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
Classification, identification, and clinical significance of Proteus, Providencia, and Morganella.
October 2000, Clinical microbiology reviews,
U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
Bactericidal activity of normal serum against bacterial cultures. II. Activity against Eschericha coli strains.
March 1960, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
Bactericidal activity of normal serum against bacterial cultures. I. Activity against Salmonella typhi strains.
February 1958, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
Occurrence and pathogenic role of Morganella-Proteus-Providencia group bacteria in human feces.
February 1986, Journal of clinical microbiology,
U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
Population-based study of Morganella-Proteus-Providencia group bloodstream infections.
September 2023, Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada,
U Nawrot, and G Mokracka-Latajka, and J Grzybek-Hryncewicz, and B Krzyzanowska, and S Jankowski
Molecular characterization of the genera Proteus, Morganella, and Providencia by ribotyping.
September 1999, Journal of clinical microbiology,
Copied contents to your clipboard!