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Nedocromil sodium in concentrations of 10(-3) to 10(-9) M dose-dependently inhibits a zymosan (2 mg/ml)-induced chemiluminescence response (CLR) of whole blood leukocytes and, to a lesser extent, phorbol myrystate acetate (PMA)-induced CLR. The count of diformazan-positive granulocytes in the zymosan-induced nitroblue tetrazolium test slightly reduced in the presence of 10(5) nedocromil sodium. PMA in a dose of 10(-9) M did not induce CLR, but brought about leukocyte priming, thus sensitizing them to secondary triggering by suboptimal zymosan concentrations (0.5 mg/ml). A subsequent stimulation of leukocytes with PMA + zymosan demonstrated that nedocromil sodium (10(-7) M) inhibited mainly priming PMA rather than the zymosan-triggering step of leukocyte activation.
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
September 1981,
Journal of the Reticuloendothelial Society,
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
January 1989,
Laboratornoe delo,
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
November 1984,
Blutalkohol,
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
August 1986,
Journal of clinical microbiology,
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
September 1989,
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ),
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
January 2007,
Luminescence : the journal of biological and chemical luminescence,
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
January 1996,
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic],
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
April 1995,
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic],
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
January 1989,
Biofizika,
D N Maianskiĭ, and
D D Tsyrendorzhiev, and
O P Makarova, and
A A Norris
January 1997,
Tsitologiia,
