Biomaterial Database

Mortality among workers at a pesticide manufacturing plant. 1995

Y Amoateng-Adjepong, and N Sathiakumar, and E Delzell, and P Cole

Department of Epidemiology, School of Public Health, University of Alabama, Birmingham 35294-0008, USA.

This study evaluated the mortality experience of 2384 workers at a plant in Colorado that produced aldrin, azodrin, vapona, and other pesticides. Subjects were followed up for a median of 29 years, from 1952 through 1990. Comparisons of the cohort's mortality rates with those of the Colorado population indicated that observed and expected numbers of deaths were similar for all causes (465 observed/473 expected) and for all cancers (113/106). Standardized mortality ratios were elevated for hepatobiliary cancer (5/2.0; standardized mortality ratio, 249, 95% confidence interval, 81 to 581), due to an excess of biliary duct/gall bladder cancer, and for pneumonia (20/13; standardized mortality ratio, 150, 95% confidence interval, 92 to 232). These increases were limited to white men in hourly jobs but were not limited to any particular production unit and did not display duration-response trends. It is unlikely that these excesses are due to occupational exposures at the plant.

UI	MeSH Term	Description	Entries
D008113	Liver Neoplasms	Tumors or cancer of the LIVER.	Cancer of Liver,Hepatic Cancer,Liver Cancer,Cancer of the Liver,Cancer, Hepatocellular,Hepatic Neoplasms,Hepatocellular Cancer,Neoplasms, Hepatic,Neoplasms, Liver,Cancer, Hepatic,Cancer, Liver,Cancers, Hepatic,Cancers, Hepatocellular,Cancers, Liver,Hepatic Cancers,Hepatic Neoplasm,Hepatocellular Cancers,Liver Cancers,Liver Neoplasm,Neoplasm, Hepatic,Neoplasm, Liver
D008297	Male		Males
D009784	Occupational Diseases	Diseases caused by factors involved in one's employment.	Diseases, Occupational,Occupational Illnesses,Disease, Occupational,Illnesse, Occupational,Illnesses, Occupational,Occupational Disease,Occupational Illnesse
D010575	Pesticides	Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.	Pesticide
D011014	Pneumonia	Infection of the lung often accompanied by inflammation.	Experimental Lung Inflammation,Lobar Pneumonia,Lung Inflammation,Pneumonia, Lobar,Pneumonitis,Pulmonary Inflammation,Experimental Lung Inflammations,Inflammation, Experimental Lung,Inflammation, Lung,Inflammation, Pulmonary,Inflammations, Lung,Inflammations, Pulmonary,Lobar Pneumonias,Lung Inflammation, Experimental,Lung Inflammations,Lung Inflammations, Experimental,Pneumonias,Pneumonias, Lobar,Pneumonitides,Pulmonary Inflammations
D002617	Chemical Industry	The aggregate enterprise of manufacturing and technically producing chemicals. (From Random House Unabridged Dictionary, 2d ed)	Industry, Chemical,Chemical Industries,Industries, Chemical
D003120	Colorado	State bounded on the north by Wyoming and Nebraska, on the east by Kansas and Nebraska, on the south by New Mexico and Oklahoma, and on the west by Utah.
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults