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Study was made of the frequency of induced and spontaneous mutations in phage T4 in RNA polymerase Escherichia coli strains. It has been shown that the rate of induced mutagenesis by base analogues increases in two rUV-mutants of phage T4 carrying mutations of the transition type, unlike the frameshift mutant which does not revert under these conditions. An increase in the level of spontaneous mutations in the phage is also found when RNA polymerase mutations are introduced into the system. The influence of mutant RNA polymerase on the mutation process is specific as no alteration of the recombination process in phage T4 has been found in E. coli strains with mutant RNA polymerase.
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
January 1975,
Genetika,
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
January 2001,
Biofizika,
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
January 1975,
Journal of biochemistry,
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
November 1972,
Virology,
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
January 1981,
Molecular & general genetics : MGG,
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
January 1974,
Basic life sciences,
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
January 1982,
Molekuliarnaia biologiia,
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
January 1983,
Methods in enzymology,
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
July 1996,
Journal of bacteriology,
E S Piruzian, and
S I Alikhanian, and
N G Iaroslavtseva
February 1993,
The Journal of biological chemistry,
