-transparent.png){kind=logo}
We investigated dopamine D2 receptors in the caudate nucleus and putamen with positron emission tomography in seven patients with narcolepsy and seven healthy controls by using [11C]raclopride as a ligand. We applied an equilibrium method and Scatchard principle to give a quantitative estimation of the number (Bmax) and dissociation constant (Kd) of the receptors. Both the Bmax and Kd were within the normal range in the caudate nucleus and putamen in narcoleptic patients. We found no evidence for increased D2 receptor binding in narcolepsy.
Related Publications
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
October 2010,
Biological psychiatry,
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
January 1993,
European journal of clinical pharmacology,
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
June 2002,
Neuropediatrics,
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
December 1986,
Science (New York, N.Y.),
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
August 1996,
Psychopharmacology,
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
January 1997,
Movement disorders : official journal of the Movement Disorder Society,
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
February 1994,
Archives of general psychiatry,
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
December 2011,
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology,
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
August 1997,
Psychopharmacology,
J O Rinne, and
C Hublin, and
M Partinen, and
H Ruottinen, and
U Ruotsalainen, and
K Någren, and
P Lehikoinen, and
A Laihinen
December 2004,
The international journal of neuropsychopharmacology,
