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By contrast to adult brain, little is known on the development of nicotinic acetylcholine receptor (nAChR) expression. Using a digoxigenin-labeled riboprobe for in situ hybridization, alpha 4 nAChR subunit mRNA expression was studied in embryonic and postnatal rat neocortex and hippocampus where it was transiently increased in neuronal subpopulations and preceded cholinergic fiber ingrowth. alpha 4 expression was increased in neocortical layer VIb between E20 and P2 and, about birth, in dentate gyrus granule cells subsequently decreasing to adult levels. nAChR mRNA expression is increased at the developing neuromuscular endplate preceding cholinergic innervation which triggers changes in non-alpha nAChR isoform expression. It has to be elucidated whether similar changes may occur in the telencephalon.
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
November 1995,
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience,
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
October 2008,
The Journal of comparative neurology,
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
May 1995,
Brain research. Molecular brain research,
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
December 2006,
Journal of chemical neuroanatomy,
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
November 1998,
Neuroscience letters,
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
November 2002,
Brain research. Developmental brain research,
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
January 2019,
Frontiers in neuroanatomy,
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
April 1995,
Cell biology international,
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
December 1999,
Brain research. Developmental brain research,
C H Ostermann, and
J Grunwald, and
A Wevers, and
D E Lorke, and
S Reinhardt, and
A Maelicke, and
H Schröder
November 2009,
Neuroscience research,
