After a short historical survey authors summarise the histological processes of the replacement of allogen spongiosa. They compare the characteristics of the autologous and homologous bone. They review the technology of the preparation of the lyophylised spongiosa. They mention the bonematrix gelatin, bone morphogenetic protein and the fibrin sealant which increases the formers effectiveness. They demonstrate their cases, some of them in detail. They pointed out the good clinical results and suggest wider application and further investigation.