Activated protein C resistance and inherited thrombosis.
1995
M Cushman, and
E G Bovill, and
R P Tracey
UI
MeSH Term
Description
Entries
D011486
Protein C
A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
D004351
Drug Resistance
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
Resistance, Drug
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013924
Thrombophlebitis
Inflammation of a vein associated with a blood clot (THROMBUS).
Phlegmasia Alba Dolens,Dolens, Phlegmasia Alba,Thrombophlebitides