A 6-month study project utilized four human subjects and a total of 63 biopsies which were obtained from gingiva treated by hand scaling, Alpha-Sonic scaling and Cavitron. These were compared with controls (untreated specimens). Microsections of soft tissues taken immediately and after 1 and 2 weeks were evaluated. The clinical acceptability of Alpha-Sonic as a working tool for periodontal scaling is to be noted.