Biomaterial Database

Effect of human chorionic gonadotropin administered early in the estrous cycle on ovulation and subsequent luteal function in cows. 1993

P M Fricke, and L P Reynolds, and D A Redmer

Department of Animal and Range Sciences, North Dakota State University, Fargo 58105.

Cows of mixed beef breeds were randomly assigned to receive one of three treatments: 1) i.v. injection of hCG on d 6 of the estrous cycle (estrus = d 0) and slaughter on d 12 to 14, 2) i.v. injection of saline on d 6 and slaughter on d 12 to 14, or 3) slaughter on d 5 to 7. Corpora lutea (CL) were collected at slaughter and weighed. A portion of each CL was cultured for 6 h with no hormone or various doses of LH (25, 50, or 100 ng/mL of medium). All cows that received an hCG injection on d 6 (Treatment 1) exhibited a luteal structure in addition to the CL present at the time of hCG administration. Thus, the following CL were evaluated: 6-d-old (induced) CL from Treatment 1 (d-6 hCG) and 13-d-old (natural) CL from Treatment 1 (d-13 hCG), 13-d-old CL from Treatment 2 (d 13), and 6-d-old CL from Treatment 3 (d 6). From d 9 to 13, daily plasma progesterone concentrations were greater (P < .01) for cows on Treatment 1 than for cows on Treatment 2. Whereas LH stimulated (P < .01) progesterone secretion regardless of treatment, progesterone secretion in vitro was greater (P < .01) for CL from saline-treated cows (Treatments 2 and 3) than for CL from hCG-treated cows (Treatment 1). No effect of hCG was observed for luteal DNA, RNA, or protein concentrations, or for luteal RNA:DNA or protein:DNA ratios.(ABSTRACT TRUNCATED AT 250 WORDS)

UI	MeSH Term	Description	Entries
D007275	Injections, Intravenous	Injections made into a vein for therapeutic or experimental purposes.	Intravenous Injections,Injection, Intravenous,Intravenous Injection
D009929	Organ Size	The measurement of an organ in volume, mass, or heaviness.	Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D010060	Ovulation	The discharge of an OVUM from a rupturing follicle in the OVARY.	Ovulations
D011374	Progesterone	The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.	Pregnenedione,Progesterone, (13 alpha,17 alpha)-(+-)-Isomer,Progesterone, (17 alpha)-Isomer,Progesterone, (9 beta,10 alpha)-Isomer
D011506	Proteins	Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.	Gene Products, Protein,Gene Proteins,Protein,Protein Gene Products,Proteins, Gene
D011897	Random Allocation	A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.	Randomization,Allocation, Random
D002417	Cattle	Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.	Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D003338	Corpus Luteum	The yellow body derived from the ruptured OVARIAN FOLLICLE after OVULATION. The process of corpus luteum formation, LUTEINIZATION, is regulated by LUTEINIZING HORMONE.	Corpora Lutea,Lutea, Corpora
D004247	DNA	A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).	DNA, Double-Stranded,Deoxyribonucleic Acid,ds-DNA,DNA, Double Stranded,Double-Stranded DNA,ds DNA
D004971	Estrus	The period in the ESTROUS CYCLE associated with maximum sexual receptivity and fertility in non-primate female mammals.