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[Treatment of angina pectoris with perhexiline maleate. Clinical evaluation in controlled double-blind study with placebo and prenylamine]. 1976

S Dalla Volta, and U Episcopo, and A Gemelli, and B Permutti

UI MeSH Term Description Entries
D008297 Male Males
D008298 Maleates Derivatives of maleic acid (the structural formula (COO-)-C
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010480 Perhexiline 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis. Perhexilene
D010880 Piperidines A family of hexahydropyridines.
D010919 Placebos Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol. Sham Treatment
D011299 Prenylamine A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1406) Corontin,Difril,Segontin
D002986 Clinical Trials as Topic Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries. Clinical Trial as Topic
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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