-transparent.png){kind=logo}
A pool of beta 1-integrin, ready to be inserted into the cleavage membranes, is present in the cytoplasm of the Xenopus egg, while its plasma membrane is devoid of this membrane protein (Gawantka et al., 1992). The underlying mechanisms that lead to this specific pattern of beta 1-integrin distribution in the egg have been investigated. beta 1-Integrin is present on the oocyte membrane throughout oogenesis. During maturation the oocyte membrane is cleared of beta 1-integrin via internalization of the protein by the oocyte. Synthesis of beta 1-integrin precursor is stimulated moderately in the maturing oocyte. At the same time processing of the precursor into the mature form of beta 1-integrin and its complexing with a putative alpha-chain is greatly accelerated. This way a maternal integrin pool accumulates in the mature oocyte. It is localized in conspicuous yolk free patches which contain large amounts of endoplasmic reticulum, Golgi complexes and smooth vesicles. We suggest that membrane vesicles harbouring the beta 1-integrin are generated in these cytoplasmic regions and that this store of vesicles provides the material source for the rapid membrane formation during cleavage.
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
June 1994,
The Biochemical journal,
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
April 1984,
The Journal of experimental zoology,
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
January 1976,
Experimental cell research,
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
July 1993,
FEBS letters,
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
June 1978,
The Journal of experimental zoology,
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
June 2001,
The Journal of surgical research,
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
July 1990,
Development (Cambridge, England),
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
January 1982,
Developmental biology,
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
October 1973,
Cell differentiation,
A H Müller, and
V Gawantka, and
X Ding, and
P Hausen
April 1979,
Archives of biochemistry and biophysics,
