Biomaterial Database

Experiences with the Linton-Nachlas and the Sengstaken-Blakemore tubes for bleeding esophageal varices. 1976

F Burcharth, and J Malmstrom

A controlled clinical trial was begun to compare the effectiveness of the Sengstaken-Blakemore tube with that of the Linton-Nachlas tube in the emergency treatment of bleeding esophageal varices. The investigation was prematurely terminated after two lethal complications with the Linton-Nachlas tube. At that time, 28 patients with 42 bleeding episodes were included. Twenty-seven were treated with the Sengstaken-Blakemore tube, with bleeding being controlled in 20; 15 were treated with the Linton-Nachlas tube, with bleeding being controlled in six. No significant statistical difference was found between the two tubes, 0.05 less than p less than 0.1, but the results encourage the use of Sengstaken-Blakemore tube in preference to the Linton-Nachlas tube, except in patients with a hiatal hernia or bleeding from fundic varices.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D004932	Esophageal and Gastric Varices	Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).	Esophageal Varices,Gastric Varices,Esophageal Varix,Gastric Varix,Varices, Esophageal,Varices, Gastric,Varix, Esophageal,Varix, Gastric
D005260	Female		Females
D006471	Gastrointestinal Hemorrhage	Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.	Hematochezia,Hemorrhage, Gastrointestinal,Gastrointestinal Hemorrhages,Hematochezias
D006489	Hemostatic Techniques	Techniques for controlling bleeding.	Hemostatic Technics,Hemostatic Technic,Hemostatic Technique,Technic, Hemostatic,Technics, Hemostatic,Technique, Hemostatic,Techniques, Hemostatic
D006548	Hernia, Diaphragmatic	Protrusion of abdominal structures into the THORAX as a result of congenital or traumatic defects in the respiratory DIAPHRAGM.	Diaphragmatic Hernia,Diaphragmatic Hernias,Hernias, Diaphragmatic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults